Results 21 to 30 of about 14,033 (212)

Red Cell Alloimmunization Among Transfused Chronic Kidney Disease Patients: A Hospital-Based Study in Southwestern Uganda [PDF]

Journal of Blood Medicine
Elizabeth A John,1 Enoch Muwanguzi,1 Robert Wagubi,1 Simon Peter Rugera,1 Charles Nkubi Bagenda,1 Rose Muhindo,2 Benson Okongo1 1Department of Medical Laboratory Science, Mbarara University of Science and Technology, Mbarara City, Uganda; 2Department of ...
John EA, Muwanguzi E, Wagubi R, Rugera SP, Bagenda CN, Muhindo R, Okongo B   +6 more
doaj   +1 more source

Transfusions in aplastic anemia patients cause HLA alloimmunization Comparisons of current and past cohorts demonstrate progress [PDF]

, 2021
Background: Transfusions are the mainstay of supportive therapy in patients with aplastic anemia (AA) and may lead to anti-human leukocyte antigen (HLA) alloimmunization, thereby also increasing the risk for donor-specific antibodies in the setting of ...
Schaub, Stefan, Volken, Thomas, Rovó, Alicia, Wehmeier, Caroline, Drexler, Beatrice, Infanti, Laura, Buser, Andreas, Julen, Katja, Holbro, Andreas, Diesch, Tamara, Passweg, Jakob R, Halter, Jörg P., Halter, Jörg P   +12 more
core   +2 more sources

Alloimmunization after platelet transfusion:Mechanisms, prevention and treatment [PDF]

, 2018
The effectiveness of platelet transfusions, an essential supportive care for mostly hemato-oncologic patients, can be diminished due to multiple causes.
Saris, A.
core   +7 more sources

Red Blood Cell Alloimmunization and Its Associated Factors among Chronic Liver Disease Patients in a Teaching Hospital in Northeastern Malaysia

Diagnostics, 2023
Red blood cell (RBC) alloimmunization is an important complication of blood transfusion. Variations in the frequency of alloimmunization have been noted among different patient populations. We aimed to determine the prevalence of RBC alloimmunization and
Siti Zaleha S. Abdullah, Mohd Nazri Hassan, Marini Ramli, Marne Abdullah, Noor Haslina Mohd Noor   +4 more
doaj   +1 more source

Alloimmunization to erythrocyte antigens in patients receiving multiple blood transfusions: Clinico-immunohematological and demographic risk factors and impact of extended red cell phenotyping

Global Journal of Transfusion Medicine, 2021
Background and Objectives: The risk of red blood cell (RBC) alloimmunization is always a concern for multi-transfused patients. Various factors have been found to be associated with alloimmunization. Alloimmunization rates were reported from 4% to 50%, 1.
Sudipta Sekhar Das, Rathindra Nath Biswas, Mahammad Safi, Rafique Uz Zaman   +3 more
doaj   +1 more source

Proinflammatory state promotes red blood cell alloimmunization in pediatric patients with sickle cell disease

Blood Advances, 2023
Key Points • Transfusion during proinflammatory events increases alloimmunization in patients with sickle cell disease, which is not mitigated by HU.• High transfusion burden and HbSS and HbSβ0–thalassemia genotypes are additional risk factors for ...
Yan Zheng, J. Gossett, Pei-Lin Chen, Martha Barton, M. Ryan, Jing Yu, G. Kang, J. Hankins, Stella T. Chou   +8 more
semanticscholar   +1 more source

Prior Immunization to an Intracellular Antigen Enhances Subsequent Red Blood Cell Alloimmunization in Mice.

Blood, 2023
Antibodies to red blood cell (RBC) alloantigens can increase morbidity and mortality in transfusion recipients. However, alloimmunization rates can vary dramatically, with some patients never generating alloantibodies following transfusion, while others ...
R. Jajosky, Seema R. Patel, Shang-Chuen Wu, K. Patel, M. Covington, M. Vallecillo-Zúniga, Diyoly Ayona, Ashley Bennett, C. Luckey, K. Hudson, J. Hendrickson, S. Eisenbarth, C. Josephson, P. Zerra, S. Stowell, C. Arthur   +15 more
semanticscholar   +1 more source

Storage differentially impacts alloimmunization to distinct red cell antigens following transfusion in mice

Transfusion, 2023
The impact of blood storage on red blood cell (RBC) alloimmunization remains controversial, with some studies suggesting enhancement of RBC‐induced alloantibody production and others failing to observe any impact of storage on alloantibody formation ...
Cheryl L. Maier, Ryan P. Jajosky, Seema R. Patel, Hans P. Verkerke, Megan D. Fuller, J. W. Allen, Patricia E. Zerra, Ross M. Fasano, S. Chonat, C. Josephson, D. Gibb, Stephanie C. Eisenbarth, C. John Luckey, K. Hudson, Jeanne E. Hendrickson, C. Arthur, Sean R. Stowell   +16 more
semanticscholar   +1 more source

Transfusions in autoimmune hemolytic anemias: Frequency and clinical significance of alloimmunization

Journal of Internal Medicine, 2023
Autoimmune hemolytic anemia (AIHA) may be associated with transfusion reactions and risk of alloimmunization.
Francesco Versino, N. Revelli, Stefania Villa, Loredana Pettine, A. Zaninoni, Daniele Prati, F. Passamonti, W. Barcellini, B. Fattizzo   +8 more
semanticscholar   +1 more source

The Development and Consequences of Red Blood Cell Alloimmunization

Annual Review of Pathology, 2022
While red blood cell (RBC) transfusion is the most common medical intervention in hospitalized patients, as with any therapeutic, it is not without risk.
C. Arthur, S. Stowell
semanticscholar   +1 more source