Results 41 to 50 of about 14,033 (212)
Clodronate Inhibits Alloimmunization Against Distinct Red Blood Cell Alloantigens in Mice
Transfusion, 2022 Alloimmunization can be a significant barrier to red blood cell (RBC) transfusion. While alloantigen matching protocols hold promise in reducing alloantibody formation, transfusion‐dependent patients can still experience RBC alloimmunization and ...
C. Arthur +16 more
semanticscholar +1 more source
Type 1 Interferon Gene Signature Promotes RBC Alloimmunization in a Lupus Mouse Model
Frontiers in Immunology, 2020 Red blood cell (RBC) transfusion exposes recipients to hundreds of unmatched minor RBC antigens. This exposure can lead to production of alloantibodies that promote clinically significant hemolytic events.
June Young Lee +8 more
doaj +1 more source
Hematology, 2021 Objectives To determine the rate of RhD-alloimmunization in injured RhD-negative patients in the age range of childbearing potential who were transfused with at least one unit of RhD-positive red blood cells (RBC) or low titer group O whole blood (LTOWB).
M. Yazer +4 more
semanticscholar +1 more source
How to avoid the problem of erythrocyte alloimmunization in sickle cell disease.
Hematology. American Society of Hematology. Education Program, 2021 Erythrocyte alloimmunization is a major barrier to transfusion in sickle cell disease (SCD) because it can lead to transfusion deadlock and the development of life-threatening hemolytic transfusion reactions (HTRs).
F. Pirenne, A. Floch, A. Habibi
semanticscholar +1 more source
Blood Advances, 2021 Chronically transfused patients with thalassemia are at risk for red cell alloimmunization. No studies have specifically examined alloimmunization after implementation of prophylactic Rh (D, C, E) and K matched red cells in a racially diverse population ...
Sarah J Waldis +7 more
semanticscholar +1 more source
Alloimmunization in sickle cell disease: changing antibody specificities and association with chronic pain and decreased survival: Alloimmunization in SCD [PDF]
, 2015 Alloimmunization remains a significant complication of transfusion and has been associated with multiple factors, including inflammation, an important pathophysiologic mechanism in sickle cell disease (SCD).
Telen, Marilyn J. +5 more
core +1 more source
EFFECTS OF CHEMOTHERAPY ON RED BLOOD CELL ALLOIMMUNIZATION IN CHILDREN [PDF]
, 2015 Background: Red cell transfusions can lead to alloimmunization; however, pediatric alloimmunization frequency has not been well studied, and it may vary among diagnostic subgroups. Subgroups such as pediatric hematology/oncology patients require numerous
SOLH, ZIAD
core +1 more source
Placenta, 2021 INTRODUCTION Maternal alloimmunization against human platelet antigen (HPA)-1a has been implied to mediate both reduced birth weight and chronic placental inflammation.
Nora Hersoug Nedberg +11 more
semanticscholar +1 more source
RhD alloimmunization – diagnostics, therapy and prophylaxis [PDF]
Introduction: The success in preventing and treating Rh D alloimmunization is a major accomplishment in modern obstetrics. The widespread use of Rh D immune globulin has led to a decline in red cell alloimmunization. Despite evidence of its effectiveness,
Izdebska, Wiktoria +9 more
core +3 more sources
Maternal red blood cell alloimmunization prevalence in the United States
Blood AdvancesKey Points • In this first national sample of RBC abs in pregnancies in the United States, 1.5% screened positive for RBC abs.• The prevalence of RBC abs increased from 2010 to 2021; RBC abs high risk for HDFN were identified in 74.3% of pregnancies.
R. Sugrue +8 more
semanticscholar +1 more source