Results 51 to 60 of about 14,033 (212)

Incidence of alloimunization in sickle cell disease: experience of a center in São Paulo [PDF]

Einstein (São Paulo), 2011
Objective: To identify the incidence of alloimmunization in sicklecell disease patients, as well as autoantibodies and the phenotypicprofile of these patients for the following erythrocyte antigengroups: Rh, Kell, Kidd, Duffy and MNS.
Ricardo Helman, Rodolfo Delfini Cançado, Cristina Olivatto   +2 more
doaj   +4 more sources

Analysis of risk factors for red blood cell alloimmunization and its incidence in hemoglobinopathy patients at a tertiary care center in Odisha, Eastern India

Asian Journal of Transfusion Science
BACKGROUND: Sickle cell disease (SCD) and thalassemia are common hemoglobinopathies in Eastern India. Regular blood transfusion in these patients leads to alloimmunization.
Somnath Mukherjee, Debasish Mishra, Ansuman Sahu, Namrata Datta, Niladri Das, Satya Prakash   +5 more
doaj   +1 more source

Hemolytic Disease of the Fetus and Newborn due to Intravenous Drug Use

American Journal of Perinatology Reports, 2016
Objectives The objective is to present a pregnancy complication associated with intravenous drug use, namely, that of red blood cell alloimmunization and hemolytic disease of the fetus and newborn.
Kara B. Markham, Scott R. Scrape, Mona Prasad, Karen Q. Rossi, Richard W. O'Shaughnessy   +4 more
doaj   +1 more source

RH genotypes and red cell alloimmunization rates in chronically transfused patients with sickle cell disease: A multisite study in the US

Transfusion
Red cell alloimmunization remains a challenge for individuals with sickle cell disease (SCD) and contributes to increased risk of hemolytic transfusion reactions and associated comorbidities.
Narek Israelyan, S. Vege, David F. Friedman, Zhe Zhang, Stacey Uter, R. Fasano, M. Yee, C. Piccone, Shannon Kelly, Jane S. Hankins, Yan Zheng, C. Westhoff, Stella T. Chou   +12 more
semanticscholar   +1 more source

Red Blood Cell Alloimmunization in Pediatric group with Beta Thalassemia: A Five-Year Experience

Global Pediatric Health, 2022
Beta-thalassemia is one of the most frequently occurring hematological disorders in [Removed for blinded peer-review]. Regular blood transfusion is required in almost all cases for management.
Kiran Minhas MBBS FCPS, Muzamil Shabana Ejaz MBBS MCPS DCH FCPS, Alaa Tukruna MD, Maryam Haider MBBS FCPS, Aabiya Arif MBBS, Sameer Saleem Tebha MBBS   +5 more
doaj   +1 more source

Altered type 1 interferon responses in alloimmunized and nonalloimmunized patients with sickle cell disease

eJHaem, 2021
Patients with sickle cell disease (SCD) have a high prevalence of RBC alloimmunization. However, underlying mechanisms are poorly understood. Given that proinflammatory type 1 interferons (IFNα/β) and interferon stimulated genes (ISGs) promote ...
Emaan Madany, June Lee, Chelsea Halprin, Jina Seo, Nicole Baca, Fataneh Majlessipour, Jeanne E. Hendrickson, Samuel H. Pepkowitz, Chelsea Hayes, Ellen Klapper, David R. Gibb   +10 more
doaj   +1 more source

Management of Red Cell Alloimmunization in Pregnancy

Obstetrics and Gynecology
Routine use of peak systolic velocity in the middle cerebral artery Doppler and cell-free DNA to determine fetal antigen status has changed the management of red cell alloimmunization in pregnancy. Rhesus immune globulin has resulted in a marked decrease
K. Moise, Elizabeth A. Abels
semanticscholar   +1 more source

Treatments for hematologic malignancies in contrast to those for solid cancers are associated with reduced red cell alloimmunization

Haematologica, 2017
Red cell alloimmunization may induce severe hemolytic side effects. Identification of risk-modifying conditions will help tailor preventative strategies.
Dorothea Evers, Jaap Jan Zwaginga, Janneke Tijmensen, Rutger A. Middelburg, Masja de Haas, Karen M.K. de Vooght, Daan van de Kerkhof, Otto Visser, Nathalie C.V. Péquériaux, Francisca Hudig, Johanna G. van der Bom   +10 more
doaj   +1 more source

Red Blood Cell Alloimmunization in Pregnancy: A Review of the Pathophysiology, Prevalence, and Risk Factors

Cureus
This review paper provides an overview of the risk factors and laboratory testing for red blood cell (RBC) alloimmunization in pregnancy. RBC alloimmunization is a significant medical issue that can cause haemolytic disease of the fetus and newborn (HDFN)
Sanusi Nurul ‘Adani, N. S. Mohd Ashari, Muhammad Farid Johan, H. Edinur, N. M. Mohd Noor, Mohd Nazri Hassan   +5 more
semanticscholar   +1 more source

Identification of genetic biomarkers for alloimmunization in sickle cell disease

, 2019
Most sickle cell disease (SCD) patients rely on blood transfusion as their main treatment strategy. However, frequent blood transfusion poses the risk of alloimmunization.
Joep W. R. Sins, France Pirenne, Kerkhoffs, Jean-Louis H, Gerritsma, Jorn J., de Boer, Martin, Sins, Joep W. R., van Bruggen, Robin, Michael W. Tanck, Karin van Leeuwen, van Leeuwen, Karin, Sanne M. Meinderts, Jean‐Louis H. Kerkhoffs, Sins, Joep W R, Robin van Bruggen, Biemond, Bart J, Anita W. Rijneveld, Karin Fijnvandraat, Meinderts, Sanne M, Jorn J. Gerritsma, Anoosha Habibi, Gerritsma, Jorn J, Meinderts, Sanne M., Ellen van der Schoot, van den Berg, Timo K, Pirenne, France, Bart J. Biemond, Rijneveld, Anita W., Kerkhoffs, Jean-Louis H., Kuijpers, Taco W., Fijnvandraat, Karin, Taco W. Kuijpers, Tanck, Michael W, Tanck, Michael W., van den Berg, Timo K., Timo K. van den Berg, Habibi, Anoosha, Rijneveld, Anita W, van der Schoot, Ellen, Martin de Boer, Biemond, Bart J., Kuijpers, Taco W   +40 more
core   +2 more sources