Results 51 to 60 of about 10,309 (223)
Prenatal Diagnosis, EarlyView.ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup +4 more
wiley +1 more source
RhD alloimmunization – diagnostics, therapy and prophylaxis
Quality in SportIntroduction: The success in preventing and treating Rh D alloimmunization is a major accomplishment in modern obstetrics. The widespread use of Rh D immune globulin has led to a decline in red cell alloimmunization.
Radoslaw Ciesielski +9 more
doaj +1 more source
The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice
EBioMedicine, 2016 Red blood cell (RBC) transfusions are essential for patients with hematological disorders and bone marrow failure syndromes. Despite ABO matching, RBC transfusions can lead to production of alloantibodies against “minor” blood group antigens.
David R. Gibb +8 more
doaj +1 more source
Plasmapheresis for the Treatment of Anti-M Alloimmunization in Pregnancy
Case Reports in Obstetrics and Gynecology, 2020 Intrauterine transfusion is the standard antenatal treatment for a fetus with severe anemia. Plasmapheresis is an alternative treatment for cases with a history of severe hemolytic disease of the fetus and newborns at less than 20 weeks of gestation ...
Yohei Maki +6 more
doaj +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir +6 more
wiley +1 more source
Evidence for a regulatory idiotypic network in the in vivo response to H-2 antigens. [PDF]
, 1985 Treatment of BALB/c mice with purified pig antiidiotype to 11-4.1 (anti-H-2Kk) monoclonal antibody has been found previously to induce the appearance of idiotype-bearing molecules (Id') in the serum of these mice, in the absence of detectable antigen ...
Bluestone, JA, Rabinowitz, R, Sachs, DH
core
Blood Advances: Immune aplastic anemia (iAA) frequently results in transfusion dependence on platelets and packed red blood cells, increasing the risk for complications.
Jibran Durrani +15 more
doaj +1 more source
Evaluation of the New Lateral Flow Card MDmulticard® Basic Extended Phenotype in Routine Clinical Practice [PDF]
, 2018 Background: Transfusion emergencies and critical situations require specifically designed devices to simplify and optimize the standard procedures. In addition, matching antigens over and above ABO-Rh-K would be beneficial. Methods: Routine blood samples
Candela-García, María-José +5 more
core +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.In Finland, implementation of targeted routine antenatal anti‐D prophylaxis (RAADP) from 2014 to 2023 resulted in a 64% reduction in maternal anti‐D immunization and fewer cases of severe hemolytic disease of the fetus and newborn requiring intrauterine transfusion, demonstrating the population‐level benefits of targeted national prophylaxis programs ...
Anna Parhamaa +8 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Background Central venous catheters (CVCs) are essential in pediatric hematology‐oncology, for the administration of chemotherapy and supportive therapy. Thrombocytopenia increases the risk of bleeding and current guidelines recommend prophylactic platelet transfusions below 40–50 × 109/L, though evidence is limited and transfusions entail ...
Alessandro Raffaele +8 more
wiley +1 more source