Results 31 to 40 of about 14,033 (212)

Red cell alloimmunization and associated risk factors in multiply transfused thalassemia patients: A prospective cohort study conducted at a tertiary care center in Northern India

Asian Journal of Transfusion Science, 2023
BACKGROUND: One of the complications of chronic transfusions in thalassemia is the development of red cell alloimmunization. AIMS: The aim of the study was to determine the frequency, specificity of red cell alloantibodies, and factors influencing ...
Brijesh Kumar Yadav, R. Chaudhary, P. Elhence, S. Phadke, K. Mandal, D. Saxena, A. Moirangthem   +6 more
semanticscholar   +1 more source

Red cell transfusion and alloimmunization in sickle cell disease

Haematologica, 2021
Red cell transfusion remains a critical component of care for acute and chronic complications of sickle cell disease. Randomized clinical trials demonstrated the benefits of transfusion therapy for prevention of primary and secondary strokes and ...
G. Linder, Stella T. Chou
semanticscholar   +1 more source

A Conceptual Framework for Optimizing Blood Matching Strategies: Balancing Patient Complications Against Total Costs Incurred

Frontiers in Medicine, 2018
Alloimmunization is currently the most frequent adverse blood transfusion event. Whilst completely matched donor blood would nullify the alloimmunization risk, this is practically infeasible.
Joost H. J. van Sambeeck, Joost H. J. van Sambeeck, Puck D. de Wit, Jessie Luken, Barbera Veldhuisen, Barbera Veldhuisen, Katja van den Hurk, Anne van Dongen, Maria M. W. Koopman, Marian G. J. van Kraaij, Marian G. J. van Kraaij, Marian G. J. van Kraaij, C. Ellen van der Schoot, Henk Schonewille, Wim L. A. M. de Kort, Wim L. A. M. de Kort, Mart P. Janssen   +16 more
doaj   +1 more source

Incidence of anti‐D alloimmunization in D‐negative individuals receiving D‐positive red blood cell transfusion: A systematic review and meta‐analysis

Vox Sanguinis, 2022
The transfusion of D‐negative red blood cells (RBCs) to D‐negative patients has been widely adopted to prevent anti‐D alloimmunization, especially in women of childbearing age.
Yanli Ji, G. Luo, Yong-Shui Fu
semanticscholar   +1 more source

Alloimmunization to minor red cell antigen leading to massive hemolysis in newly diagnosed thalassemia intermedia

Global Journal of Transfusion Medicine, 2021
Alloimmunization to red cell antigens is a taxing complication of thalassemia major and intermedia patients who receive routine blood transfusions. The data on alloimmunization in beta-thalassemia are sparse from developing countries.
Satyam Arora, Ravi Shankar, Seema Dua, Nita Radhakrishnan   +3 more
doaj   +1 more source

Red blood cell alloimmunization and other transfusion-related complications in patients with transfusion-dependent thalassemia: a multi-center study in Thailand

Transfusion, 2022
Thalassemia is a common genetic disease in Southeast Asia. Red blood cell (RBC) transfusion is an essential treatment for severe forms of thalassemia. We performed a study to demonstrate RBC alloimmunization and other transfusion‐related complications in
N. Teawtrakul, Duantida Songdej, Chattree Hantaweepant, A. Tantiworawit, Supanun Lauhasurayotin, K. Torcharus, Pornpun Sripornsawan, P. Sutcharitchan, P. Surapolchai, P. Komvilaisak, Supawee Saengboon, B. Pongtanakul, P. Charoenkwan   +12 more
semanticscholar   +1 more source

Red cell alloimmunization is associated with increased health care costs, longer hospitalizations, and higher mortality

Blood Advances, 2022
High rates of alloimmunization have been observed among patients requiring chronic red blood cell (RBC) transfusions, especially those with sickle cell disease (SCD) and thalassemia. 1-3 Alloimmunization in SCD increases the risk of hemolytic transfusion
Elisabet Viayna, Eric A. Gehrie, C. Blanchette, G. Meny, Ghislain T. Noumsi, Maria Huber, M. C. Runken   +6 more
semanticscholar   +1 more source

Red blood cell alloimmunization in Iran: A Comprehensive review of the literature

Asian Journal of Transfusion Science, 2020
Background: Alloimmunization is an immune response against foreign antigens which introduced into the body through transfusion, pregnancy, or transplantation. This phenomenon is a big challenge in patients, which require regular transfusions.
Maryam Sadat Hosseini, Leila Jafari, Reza Shiri Heris, Ahmad Gharehbaghian   +3 more
doaj   +1 more source

HLA Class II regulation of immune response in sickle cell disease patients: Susceptibility to red blood cell alloimmunization (systematic review and meta‐analysis)

Vox Sanguinis, 2022
Sickle cell disease (SCD) patients are commonly treated with red blood cell (RBC) transfusion. Pretransfusion tests commonly involve limited serological antibody testing.
Karmen Wong, W. Lai, D. Jackson
semanticscholar   +1 more source

Red cell alloimmunization in pregnancy: a study from a premier tertiary care centre of Western India

Obstetrics & Gynecology Science, 2022
Objective The study was conducted to determine the frequency of alloimmunization to various blood group antibodies in pregnant women, and the risk of hemolytic disease in the fetus and newborn.
Meenakshi Gothwal, Pratibha Singh, A. Bajpayee, Neha Agrawal, Garima Yadav, Charu Sharma   +5 more
semanticscholar   +1 more source