Results 131 to 140 of about 43,931 (305)

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

Productivity Growth in Food Crop Production in Imo State, Nigeria [PDF]

open access: yes
The study examined the productivity growth in food crop production in Imo State with emphasis on the decomposition of total factor productivity into technical progress, changes in technical and allocative efficiency and scale effects.
Nwachukwu, Ifeanyi N.   +2 more
core   +1 more source

Rotation of Crystal Seed During Early Stages of Growth Reveals the Anisotropy of Glass Matrix

open access: yesAdvanced Science, Volume 13, Issue 29, 22 May 2026.
Molecular dynamics simulations reveal that crystal seeds can spontaneously rotate within glass at high temperatures due to anisotropic forces at the glass‐crystal interface. This rotation challenges the long‐held view of glass as an isotropic solid and highlights how atomic‐scale inhomogeneities can influence crystal growth and microstructure of LiNbO3‐
R. Thapa   +4 more
wiley   +1 more source

DO MACROECONOMIC SHOCKS IMPACT THE ECONOMIC EFFICIENCY OF SMALL FARMERS? THE CASE OF WETLAND RICE FARMERS IN INDONESIA [PDF]

open access: yes
The economic efficiency of Indonesian rice farmers was lower and more variable during than before the macroeconomic crisis. Specifically, larger declines in technical efficiency were not offset by smaller improvements in allocative efficiency.
Fabiosa, Jacinto F.   +2 more
core   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

EFFICIENCY ANALYSIS OF HOSPITALS IN THE GREAT PLAINS: AN URBAN-RURAL COMPARISON [PDF]

open access: yes
This study examined the efficiency of a sample of hospitals in the Great Plains using a nonparametric approach. Technical efficiency was less than either allocative or scale efficiency.
Featherstone, Allen M.   +2 more
core   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang   +8 more
wiley   +1 more source

Estimating Economic Efficiency in Paddy Farms: A Case of Northwest Selangor IADP [PDF]

open access: yes, 1996
Economic efficiency can be measured as allocative and technical efficiency. A study to measure the technical, allocative and economic efficiency of paddy farms using the probabilistic frontier production function was carried out.
Latiff, Ismail, Radam, Alias
core  

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

open access: yesAdvanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka   +3 more
wiley   +1 more source

Allocative efficiency and traders' protection under zero intelligence behavior [PDF]

open access: yes
This paper studies the continuous double auction from the point of view of market engineering: we tweak a resampling rule often used for this exchange protocol and search for an improved design.
Lucia Milone   +2 more
core  

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