The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui +9 more
wiley +1 more source
The Emergence of Applied Artificial Intelligence in the Realm of Value Based Musculoskeletal Care. [PDF]
Hunter J, Dentino P, Jayakumar P.
europepmc +1 more source
Autonomous High‐Throughput Characterization of Liquid‐Liquid Phase Behavior
This study introduces an automated dual modality platform, combining asymmetric capacitance deviation and multiangle turbidimetry, for high‐throughput characterization of liquid‐liquid phase behavior across chemically diverse fluid systems. The platform enables miscibility classification, resolution of phase separation kinetics and emulsion stability ...
Tarek Eid +3 more
wiley +1 more source
Performance of Greek Public Hospitals Before and After the Economic Recession and the Pandemic: Application of a Novel Cost Malmquist Index for Comparing Productivity Across Multiple Groups. [PDF]
Fourlopoulou A +3 more
europepmc +1 more source
High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan +11 more
wiley +1 more source
Reconsidering the use of race, sex, and age in clinical algorithms to address bias in practice: A discussion paper. [PDF]
Panagides R, Keim-Malpass J.
europepmc +1 more source
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo +16 more
wiley +1 more source
The valuation of older adult homecare services under a joint medical-social budgetary perspective. [PDF]
Leung E +5 more
europepmc +1 more source
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai +11 more
wiley +1 more source
Policy lessons regarding medical security for rare diseases inChina: Insights from Zhejiang Province through the multiplestreams framework. [PDF]
Wang M, Rong C, Wang P.
europepmc +1 more source

