Allodynia and Pinprick Hypesthesia in Acute Herpes Zoster, and the Development of Postherpetic Neuralgia [PDF]
Maija Haanpää+2 more
openalex +1 more source
Abstract figure legend Transient receptor potential ankyrin 1 (TRPA1) and melastatin 3 (TRPM3) activation regulate pre‐ and postsynaptic Ca2+ concentrations and synaptic activity in the dorsal horn of the spinal cord. Left: a model that describes how activation of TRPA1 and TRPM3 channels induces an influx of Ca2+ in the central terminals of sensory ...
Yaroslav E. Andrianov+10 more
wiley +1 more source
Antagonism of the Melanocortin System Reduces Cold and Mechanical Allodynia in Mononeuropathic Rats [PDF]
Dorien H. Vrinten+3 more
openalex +1 more source
Abstract figure legend Previous work in humans and rodents has identified transcutaneous spinal cord stimulation as a promising strategy to reduce spasticity and hyperreflexia after spinal cord injury. The objective of this study was to deliver stimulation protocols with the intensity set (1) above motor threshold, (2) below motor threshold or (3 ...
Dillon C. Malloy+2 more
wiley +1 more source
The Role of Peripheral N-Methyl-D-Asparate (NMDA) Receptors in Itch and Pain: A Narrative Review. [PDF]
ABSTRACT Background and Objective NMDA receptors, predominantly located in the central nervous system and known for their roles in synaptic plasticity and central sensitisation of pain and itch, are also expressed in peripheral sensory neurons. Emerging evidence suggests that peripheral NMDA receptors contribute to pathological pain and potentially ...
Tanaka R+3 more
europepmc +2 more sources
Synergistic Effect between Intrathecal Non-NMDA Antagonist and Gabapentin on Allodynia Induced by Spinal Nerve Ligation in Rats [PDF]
Shao-Rui Chen+3 more
openalex +1 more source
The effect of environment on post surgical overall well-being and pain sensitivity in an animal model [PDF]
With chronic post surgical pain affecting up to one third of patients undergoing surgeries and the price of treatment being astoundingly high there has been a transition in research to investigate and identify risk factors. Through identification of risk
Reddy, Archana
core +1 more source
Local inhibitory effects of dynorphin A-(1–17) on capsaicin-induced thermal allodynia in rhesus monkeys [PDF]
Mei‐Chuan Ko+4 more
openalex +1 more source
Adrenergic Control of P2Y6 Receptor‐Dependent Phagocytosis in Rodent and Human Microglia
Main Points Adrenergic signaling through ADRB2 modulates phagocytosis in microglia Crosstalk between ADRB2 and P2Y6 receptors conserved in rodent and human microglia ADRB2 activation inhibits both P2Y6 function and gene expression ABSTRACT Microglia, the resident immune cells of the central nervous system (CNS), are in constant survey of their ...
Thomas Deluc+10 more
wiley +1 more source
Banulata Gopalsamy, Ahmad Akira Omar Farouk, Tengku Azam Shah Tengku Mohamad, Mohd Roslan Sulaiman, Enoch Kumar Perimal Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang ...
Gopalsamy B+4 more
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