Results 161 to 170 of about 52,858 (307)
IDD and OA is caused by various mechanisms, creating a vicious cycle that impairs disc function. Nanozymes and nano‐enzyme delivery systems offer innovative therapies by targeting these underlying mechanisms, such as anti‐inflammatory therapy, ECM repair, cellular dysfunction and antioxidant therapy, providing a promising approach to restoring tissue ...
Lei Peng+4 more
wiley +1 more source
A Unique Representation of Heat Allodynia in the Human Brain [PDF]
Jürgen Lorenz+5 more
openalex +1 more source
Evidence of Involvement of the Calcitonin Gene‐Related Peptide in Restless Legs Syndrome
Abstract Background Restless legs syndrome (RLS) is a common sensory‐motor disorder characterized by an urge to move the legs, often with unpleasant sensations, particularly during rest. Current treatments include iron supplementation, dopamine agonists, and opioids, but new therapeutic approaches are needed.
Maria P. Mogavero+8 more
wiley +1 more source
Tumor Necrosis Factor-α Induces Mechanical Allodynia after Spinal Nerve Ligation by Activation of p38 MAPK in Primary Sensory Neurons [PDF]
Maria Schäfers+3 more
openalex +1 more source
Abstract An 11‐year‐old, female West Highland white terrier presenting cough, emesis, diarrhoea and hyporexia refractory to symptomatic treatment was subjected to endoscopy showing increased palatine tonsil region. Biopsy findings revealed a carcinoma. Computed tomography also showed an increased right medial retropharyngeal lymph node dorsally related
Jiuli R. S. de Salles+2 more
wiley +1 more source
Chronic pain management in a dairy cow with deep digital sepsis
Abstract This case report describes a cow with a penetrating foreign body in the sole horn of its medial claw of the right forelimb, leading to sequestration and necrosis of the pedal bone and subsequent chronic pain. The surgical interventions, multimodal pain management and development of the gait pattern over more than 6 weeks are described. The cow
Jasmin Laschinger, Johann Kofler
wiley +1 more source
The Effect of alpha2 Adrenergic Agonists and Norepinephrine on Mechanical Allodynia by Freund's Complete Adjuvant Induced Inflammation in Rats [PDF]
Mi Ae Cheong+7 more
openalex +1 more source
CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation
Abstract The 5th CORONIS Symposium, held during the 2023 Congress of the European Association for Vision and Eye Research (EVER), highlighted the growing importance of ocular surface innervation in eye surface disorders. This article summarises the insights and perspectives shared during the symposium, which focused on the clinical relevance of ocular ...
Anat Galor+10 more
wiley +1 more source
MS4A7 promotes M1 microglial polarization and neuroinflammation in SCI via the cGAS‐STING‐NLRP3 axis, highlighting it as a therapeutic target for neuroprotection and recovery enhancement. Downregulation of MS4A7 helped alleviate pain‐related behaviors and improve locomotor recovery.
Xiangrui Li+6 more
wiley +1 more source