A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease
Acta Ophthalmologica, Volume 103, Issue 6, Page e346-e363, September 2025.Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia +4 more
wiley +1 more source
Results from a randomized, controlled trial on efficacy and tolerability of a 5% Lidocaine-Medicated Plaster vs. Pregabalin in patients with Post-Herpetic Neuralgia (PHN) and Painful Diabetic Polyneuropathy (DPN) [poster] [PDF]
No abstract ...
Baron, R. +4 more
core
, 2018 Background: The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life.
Elsadek, Bakheet, Maqboul, Ahmad
core +2 more sources
Presurgical ketoprofen, but not morphine, dipyrone, diclofenac or tenoxicam, preempts post-incisional mechanical allodynia in rats [PDF]
, 2002 W.A. Prado, Rosângela Pontes
openalex +1 more source
Where Does It All Itch? Exploring the Characteristics of Pruritus in Small Fiber Neuropathy
Journal of the Peripheral Nervous System, Volume 30, Issue 3, September 2025.ABSTRACT Background Chronic itch, or pruritus, is a common discomfort of the skin. Chronic itch has been described as a symptom of small fiber neuropathy (SFN), a disorder affecting the small myelinated Aδ‐ and unmyelinated C‐fibers. While prior studies report itch rates in SFN ranging from 63%–68%, a distinct pattern has not been identified.
Dennis Kool +3 more
wiley +1 more source
Tumor Necrosis Factor-α Induces Mechanical Allodynia after Spinal Nerve Ligation by Activation of p38 MAPK in Primary Sensory Neurons [PDF]
, 2003 Maria Schäfers +3 more
openalex +1 more source
Journal of the Peripheral Nervous System, Volume 30, Issue 3, September 2025.ABSTRACT Background and Aims Skin biopsies are the primary diagnostic test for small fiber neuropathy, but recently corneal confocal microscopy (CCM) has been developed as an alternative. We compared the correlations of each of these morphometric assessments with peripheral nerve function evaluated through comprehensive quantitative sensory testing ...
Farah A. Ghadban +8 more
wiley +1 more source
The Effect of alpha2 Adrenergic Agonists and Norepinephrine on Mechanical Allodynia by Freund's Complete Adjuvant Induced Inflammation in Rats [PDF]
, 2003 Mi Ae Cheong +7 more
openalex +1 more source
Decoding Pain: Next‐Generation In Vitro Systems for Mechanistic Insights and Drug Discovery
The FASEB Journal, Volume 39, Issue 16, 31 August 2025.Developing an in vitro pain model that mimics essential features of the in vivo pain circuit requires careful consideration of multiple components and choices. These include selecting the cellular population for the model, choosing from the origin of nociceptors and other cells that are cultured, deciding between 3D or 2D dimensions, designing the ...
Dara Khosrowshahi +2 more
wiley +1 more source