Results 201 to 210 of about 57,089 (325)

Tuina Inhibits Synaptic Plasticity Through the Astrocytic NDRG2/GLT‐1 Pathway to Alleviate Neuropathic Pain

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT While Tuina has demonstrated clinical efficacy in alleviating neuropathic pain (NP) induced by peripheral nerve injury, the underlying molecular mechanisms remain unclear. Synaptic plasticity in the spinal dorsal horn (SDH) is a key regulator of pain processing, wherein astrocytes play a central role.
Huanzhen Zhang, Lechun Chen, Jingjing Jiang, Limei Huang, Hongye Huang, Lanting Huang, Shuijin Chen, Zhigang Lin   +7 more
wiley   +1 more source

Prenatal alcohol exposure induces circular and linear long non-coding RNAs, and protein-coding genes linked to proinflammatory neuroimmune function, promoting nerve injury-induced allodynia following morphine treatment. [PDF]

Neuropharmacology
Pritha AN, Pasmay AA, Jones AN, Carter JR, Noor S.   +4 more
europepmc   +1 more source

Disrupted Sensorimotor Network Integration in Women With Fibromyalgia Revealed by Resting‐State Functional MRI

Journal of Neuroimaging, Volume 36, Issue 1, January/February 2026.
ABSTRACT Background and Purpose Fibromyalgia (FM) is a chronic syndrome characterized by widespread musculoskeletal pain, hypersensitivity, and cognitive impairments. Alterations in brain functional connectivity have been suggested as possible mechanisms underlying pain amplification in these patients.
Gina Rodrigues de Oliveira, Tamires Morett Gama, Lucas Rego Ramos, Marcos Fabio DosSantos   +3 more
wiley   +1 more source

Spinal Mincle activation as a new model of neuroinflammation-associated neuropathic pain: comparison with spinal nerve ligation. [PDF]

Korean J Pain
Yang J, Kim WM, Jeong S, Bae HB, Choi JI.   +4 more
europepmc   +1 more source

Differences in Plasma Exposure of Cannabidiol and Cannabidiolic Acid Following Oral Administration to Horses

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 1, Page 22-32, January 2026.
ABSTRACT There has been a growing interest in the use of cannabinoids in horses in recent years. Several studies have reported on the pharmacokinetics of cannabidiol (CBD) in horses. However, cannabidiolic acid (CBDA) has received less attention, despite limited evidence suggesting clinically beneficial effects in other species.
Carl Ekstrand, Peter Michanek, Elin Hernlund, Ronette Gehring, Kristin Spjut, Matilda Salomonsson   +5 more
wiley   +1 more source

Swimming exercise alleviates peripheral neuropathic pain by downregulating FTO and promoting m⁶A methylation of miR-183. [PDF]

J Headache Pain
Zheng YN, Zheng YL, Liu H, Ren SQ, Guo SJ, Sun T, Guan JY, Shi YQ, Chen PJ, Wang XQ.   +9 more
europepmc   +1 more source

The Use of Botulinum Toxin Injections in Peripheral Neuropathic Pain: A Systematic Review of Efficacy and Safety Outcomes

Pain Research and Management, Volume 2026, Issue 1, 2026.
Peripheral neuropathic pain (PNP), a chronic condition resulting from nerve damage and characterized by altered sensory signaling and central sensitization, poses significant therapeutic challenges. Botulinum toxin (BTX), known for neuromuscular blockades, also exhibits analgesic properties, prompting its investigation for PNP management.
Domenico Antonio Restivo, Andrea Calderone, Angelo Quartarone, Rocco Salvatore Calabrò, Antongiulio Bruschetta, Stefano Tamburin   +5 more
wiley   +1 more source

Dissecting out migraine complexity through comprehensive analysis of allodynia [PDF]

, 2018
Roberto De Icco, Cristina Tassorelli
openalex   +1 more source

Targeting prostaglandin E₂ receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation. [PDF]

Nat Commun
Nassini R, Landini L, Marini M, Chieca M, Souza Monteiro de Araújo D, Montini M, Pensieri P, Abruzzese VD, De Siena G, Zhang J, Bellantoni E, De Giorgi V, Romitelli A, Brancolini G, Tonello R, Peach CJ, Mastricci A, Scuffi I, Tesi M, Jensen DD, Schmidt BL, Bunnett NW, De Logu F, Geppetti P.   +23 more
europepmc   +1 more source

Exploring the Changes in Pain Quality, Mechanical Allodynia, and Tactile Sensibility in Women With Persistent Postpartum Perineal Pain Treated With Somatosensory Rehabilitation: A Retrospective Case Series. [PDF]

Cureus
Quintal I, Goulet L, Dyer JO, Bourbonnais D, Morin M.   +4 more
europepmc   +1 more source