Results 201 to 210 of about 66,158 (349)
Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang+9 more
wiley +1 more source
Pain Coping in Patients With Chronic Migraine and Medication Overuse Headache
Pain Coping in patients with Chronic Migraine and Medication Overuse. ABSTRACT Background Chronic migraine (CM) is a leading cause of disability and often linked to medication overuse headache (MOH). Psychological factors, such as pain coping, may contribute to chronification and medication overuse.
Thomas C. van den Hoek+4 more
wiley +1 more source
Nerve Injury Induces a Tonic Bilateral μ-Opioid Receptor–mediated Inhibitory Effect on Mechanical Allodynia in Mice [PDF]
Heikki Mansikka+5 more
openalex +1 more source
Role of NGF and capsaicin-sensitive innervation in TNBS-induced chronic colonic allodynia
Laure Delafoy+3 more
openalex +1 more source
Referred Cutaneous Allodynia in a Migraine Patient without Simultaneous Headache [PDF]
Avi Ashkenazi, C LoPinto, WB Young
openalex +1 more source
Molecular Mechanisms of Chronic Pain and Therapeutic Interventions
We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li+8 more
wiley +1 more source
The Modification for Allodynia via Adenosine A_1 Receptor
Ichiro Kawano
openalex +2 more sources
NLRP3 Inflammasome activation drives inflammatory responses through the production and activation of pro‐inflammatory cytokines. Repurposing sulphonylureas and their derivatives to target NLRP3 may act as adjunct therapeutics for autoimmune conditions. ABSTRACT A rapid and cost‐effective arm of the drug discovery and development process is finding new ...
Jasen Elford+4 more
wiley +1 more source
This study examined in mice whether limaprost, a prostaglandin E1 analog, would relieve allodynia induced by chemotherapeutic agents. Single intraperitoneal injections of paclitaxel, oxaliplatin, and vincristine sulfate induced and gradually increased ...
Punam Gauchan+4 more
doaj
Nociception and Allodynia/Hyperalgesia Induced by Intrathecal Administration of Fenvalerate
Junzo Kamei+4 more
openalex +1 more source