Study of alloferon, a novel immunomodulatory antimicrobial peptide (AMP), and its analogues [PDF]
Frontiers in PharmacologyAntimicrobial peptides (AMPs) are widely distributed throughout the biosphere and represent a class of conserved peptide molecules with intrinsic antimicrobial properties. Their broad-spectrum antimicrobial activity and low risk to induce resistance have
Ye Zhao
exaly +10 more sources
Alloferon-1 ameliorates acute inflammatory responses in λ-carrageenan-induced paw edema in mice [PDF]
Scientific Reports, 2022 Alloferon-1 have been proposed as an effective peptide to enhance antitumoral immunity, antiviral defense and anti-inflammatory activity. This work aimed to assess anti-inflammatory effects of alloferon-1 against acute inflammation and histopathological ...
Ye Zhao
exaly +7 more sources
Alloferon Affects the Chemosensitivity of Pancreatic Cancer by Regulating the Expression of SLC6A14 [PDF]
Biomedicines, 2022 Pancreatic cancer (PCa), one of the most malignant solid tumors, has a high mortality rate. Although there have been many trials of chemotherapeutic drugs such as gemcitabine, the mortality rates remain significantly higher than for other types of cancer.
Go Cheol Hyeon, Jae Seung Kang
exaly +7 more sources
Alloferon and IL-22 receptor expression regulation on the pathogenesis of imiquimod-induced psoriasis [PDF]
Scientific ReportsPsoriasis is an immune-mediated inflammatory skin disease. IL-22, a proinflammatory cytokine, is implicated in psoriasis pathogenesis; however, there is currently no established biological treatment targeting IL-22 or its receptor, IL-22Rα.
Chong Won Choi
exaly +6 more sources
Effects of alloferon and its analogues on reproduction and development of the Tenebrio molitor beetle [PDF]
Scientific ReportsAs the most numerous group of animals on Earth, insects are found in almost every ecosystem. Their useful role in the environment is priceless; however, for humans, their presence may be considered negative or even harmful.
Karolina Walkowiak-Nowicka +5 more
doaj +5 more sources
Virus-associated chronic endometritis: treatment options [PDF]
Гинекология, 2022 Aim. To evaluate the effectiveness of Alloferon (Allokin-alfa) in the complex treatment of virus-associated chronic endometritis (CE) in patients with infertility, papillomavirus infection (PVI) persisting in the uterine cavity, and recurrent herpes ...
Natalia I. Tapilskaya +9 more
doaj +3 more sources
THE IMPACT OF THE METHOD OF PREVENTION OF INTRAUTERINE INFECTION ON THE STATE OF NONSPECIFIC IMMUNITY IN PREGNANT WOMEN WITH RELAPSING HERPETIC INFECTION AND THEIR CHILDREN [PDF]
Журнал инфектологии, 2018 Purpose of the study: to assess the state of nonspecific immunity in women with relapsing herpetic infection, planning pregnancy, period of gestation, from infants and children in the first six months of life, depending on the method of prophylaxis of ...
M. A. Ovchinnikova +3 more
doaj +3 more sources
Smart materials for drug delivery and cancer therapy
VIEW, Volume 2, Issue 2, April 2021., 2021 Smart Materials in Drug Delivery have attracted considerable attention for precision cancer chemotherapy as the footstone of stimuli‐responsive nanocarriers. Numerous smart materials are delicately designed with time‐/space‐controlled drug release while responsive to either endogenous or exogenous signals.
Yao Yang +4 more
wiley +1 more source
Modulation of immune responses using adjuvants to facilitate therapeutic vaccination
Immunological Reviews, Volume 296, Issue 1, Page 169-190, July 2020., 2020 Abstract Therapeutic vaccination offers great promise as an intervention for a diversity of infectious and non‐infectious conditions. Given that most chronic health conditions are thought to have an immune component, vaccination can at least in principle be proposed as a therapeutic strategy.
Virgil Schijns +18 more
wiley +1 more source
ALLOKIN-ALPHA - NEW APPROACHES IN THE TREATMENT OF CHRONIC VIRUS EPSTEIN-BARR INFECTIONS
Вопросы вирусологии, 2019 Introduction. Epstein-Barr virus causes recurrent infectious mononucleosis-like symptoms. Today it is shown that the poisons of insects and animals are rich sources of antimicrobial substances (peptides) and contain a wide range of active biological ...
I. A. Rakitianskaya +3 more
doaj +1 more source