Results 11 to 20 of about 172 (108)
ФармакоэкономикаBackground. Alloferon is a naturally occurring peptide that exhibits pronounced antiviral and anti-inflammatory properties. By inducing interferon biosynthesis, alloferon activates lymphocyte immunity.Objective: To systematize all available scientific ...
O. A. Gromova, I. Yu. Torshin
doaj +2 more sources
Anti-inflammatory Effect of Alloferon on Ovalbumin-induced Asthma. [PDF]
Immune Netw, 2015 Asthma is a well-known inflammatory lung disease; however, the specific underlying mechanism is largely unknown. We previously demonstrated that alloferon effectively downregulates pulmonary inflammation. In this study, we examined whether alloferon has a therapeutic effect on asthma.
Jeon J, Kim Y, Kim H, Kang JS, Lee WJ.
europepmc +4 more sources
Alloferon Alleviates Dextran Sulfate Sodium-induced Colitis. [PDF]
Immune Netw, 2015 Dysfunction of gut immune regulation is involved in mucosal damage in inflammatory bowel disease (IBD). However, there is still no efficacious immune-regulator for the treatment of IBD. Alloferon is a novel immune-modulatory peptide that was originally isolated from infected insects.
Kim H, Im JP, Kim JS, Kang JS, Lee WJ.
europepmc +4 more sources
Alloferon and Zanamivir Show Effective Antiviral Activity against Influenza A Virus (H1N1) Infection In Vitro and In Vivo. [PDF]
Int J Mol Sci, 2022 The use of vaccines is the most effective and reliable method for the prevention of viral infections. However, research on evaluation of effective therapeutic agents for use in treatment after infection is necessary. Zanamivir was administered through inhalation for treatment of pandemic influenza A/H1N1 in 2009.
Lee D +10 more
europepmc +3 more sources
Effect of alloferon 1 on central nervous system in rats [PDF]
Pharmacological Reports, 2010 Alloferon 1 is an insect-derived peptide with potent antimicrobial and antitumor activity. It was isolated from blood of an experimentally infected insect, the blow fly Callifora vicina. Synthetic alloferon 1 reveals a capacity to stimulate activity of NK cells and synthesis IFN in animal and human models.
Monika, Rykaczewska-Czerwińska +5 more
openaire +3 more sources
Mechanisms of Maggot‐Induced Wound Healing: What Do We Know, and Where Do We Go from Here?
Evidence-Based Complementary and Alternative Medicine, Volume 2014, Issue 1, 2014., 2014 Medicinal maggots are believed to have three major mechanisms of action on wounds, brought about chemically and through physical contact: debridement (cleaning of debris), disinfection, and hastened wound healing. Until recently, most of the evidence for these claims was anecdotal; but the past 25 years have seen an increase in the use and study of ...
Ronald A. Sherman, Edwin L. Cooper
wiley +1 more source
ALLOKIN-ALPHA - NEW APPROACHES IN THE TREATMENT OF CHRONIC VIRUS EPSTEIN-BARR INFECTIONS
Вопросы вирусологии, 2019 Introduction. Epstein-Barr virus causes recurrent infectious mononucleosis-like symptoms. Today it is shown that the poisons of insects and animals are rich sources of antimicrobial substances (peptides) and contain a wide range of active biological ...
I. A. Rakitianskaya +3 more
doaj +1 more source
Recent Advances in Developing Insect Natural Products as Potential Modern Day Medicines
Evidence-Based Complementary and Alternative Medicine, Volume 2014, Issue 1, 2014., 2014 Except for honey as food, and silk for clothing and pollination of plants, people give little thought to the benefits of insects in their lives. This overview briefly describes significant recent advances in developing insect natural products as potential new medicinal drugs.
Norman Ratcliffe +3 more
wiley +1 more source
Antiviral effect of Alloferon on Kaposi's sarcoma‐associated herpesvirus
The FASEB Journal, 2008 Kaposi's sarcoma‐associated herpesvirus (KSHV) is a human gammaherpesvirus that is associated with the development of Kaposi's sarcoma and primary effusion lymphoma. KSHV establishes two alternate genetic life cycle programs upon infection of its host cells, which maintain a latent infection in infected cells but undergo lytic reactivation in response ...
Na Eun Lee +10 more
openaire +1 more source
Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic
Journal of Peptide Science, Volume 30, Issue 1, January 2024.This review describes the main physicochemical characteristics of antimicrobial peptides, with particular focus on peptides derived from amphibian skin. Summarizing the various antiviral activities of these peptides and the underlying mechanism, this review emphasizes the high potential of these small molecules for the development of new antiviral ...
Maria Rosa Loffredo +3 more
wiley +1 more source