Results 1 to 10 of about 50,413 (165)

Allogeneic hematopoietic stem cell transplantation in ERCC6L2 disease. [PDF]

Blood Adv
Abstract The hallmark of ERCC6L2 disease (ED) is a highly penetrant progression from bone marrow failure to erythroid-predominant, TP53-mutated myeloid malignancy with a dismal prognosis. Allogeneic hematopoietic stem cell transplant (HSCT) remains the only potentially curative option, but concerns exist ...
Hakkarainen M, Sicre de Fontbrune F, Kaaja I, Douglas S, Dalle JH, Risitano AM, Kulasekararaj A, Alsultan A, Cutler C, Ho VT, Hellström-Lindberg E, Mielke S, Myhre AE, Rihani R, Shanap MA, Hashem H, Shimamura A, Rowe RG, Auer F, Beier F, Desnica L, Hough R, Ali Jafri SR, Ayas M, Jardine L, Mellid EF, Corrales I, Richardson D, Özbek NY, Zaniewska-Tekieli A, Gozdzik J, Ryhänen S, Niinimäki R, Jahnukainen K, Salmenniemi U, Kilpivaara O, Wartiovaara-Kautto U.   +36 more
europepmc   +5 more sources

The Outcomes of Myeloid Sarcoma in 64 Pediatric Patients and the Impact of Allogeneic Hematopoietic Stem Cell Transplantation on Treatment Results [PDF]

Children
Background: Myeloid sarcoma (MS) is a malignant extramedullary tumor that occurs in patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or chronic myeloid leukemia (CML).
Magdalena Samborska, Jolanta Skalska-Sadowska, Jacek Wachowiak, Małgorzata Czogała, Walentyna Balwierz, Szymon Skoczeń, Natalia Bartoszewicz, Jan Styczyński, Tomasz Ociepa, Tomasz Urasiński, Grażyna Wróbel, Krzysztof Kałwak, Katarzyna Muszyńska-Rosłan, Anna Szmydki-Baran, Iwona Malinowska, Paweł Łaguna, Agnieszka Mizia-Malarz, Renata Tomaszewska, Tomasz Szczepański, Agnieszka Chodała-Grzywacz, Grażyna Karolczyk, Lucyna Maciejka-Kembłowska, Marta Kozłowska, Ninela Irga-Jaworska, Katarzyna Mycko, Wanda Badowska, Katarzyna Bobeff, Wojciech Młynarski, Radosław Chaber, Joanna Zawitkowska, Katarzyna Drabko, Katarzyna Derwich   +31 more
doaj   +2 more sources

A study on some factors affecting CMV reactivation in allogeneic hematopoietic stem cells transplantation [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2021
Background: In developing countries, cytomegalovirus (CMV) seropositivity has been widely propagated. Following hematopoeitic stem cell transplantation, the apparent risk of CMV reactivation increases.
Metwally Metwally, Mohamed El-Shanshory, Nanis Allam, Raafat Soliman, Hamdy Abu Ouf   +4 more
doaj   +1 more source

Comorbidity Index in Predicting Toxicity and Mortality Risk among patient Undergoing Hematopoietic Stem Cell Transplantation [PDF]

Egyptian Journal of Health Care, 2022
: Despite current improvement in supportive care, mortality after hematopoietic stem cell transplantation remains high. Caring for patients undergoing hematopoietic stem cell transplantation is one of the most challenging in nursing subspecialities. Aim:
Dina Mohamed Maarouf, Gamal El-dein Mohamed, Amany Mohamed Safwat, Sara Abdelkader Abdelfattah   +3 more
doaj   +3 more sources

Allogeneic hematopoietic stem-cell transplantation for myelofibrosis [PDF]

Therapeutic Advances in Hematology, 2020
Myelofibrosis is one of the Philadelphia chromosome (Ph)-negative myeloproliferative neoplasms with heterogeneous clinical course. Though many treatment options, including Janus kinase (JAK) inhibitors, have provided clinical benefits and improved survival, allogeneic hematopoietic stem-cell transplantation (AHSCT) remains the only potentially curative
Lining Zhang, Fan Yang, Sizhou Feng
openaire   +3 more sources

Optimizing Allogeneic Grafts in Hematopoietic Stem Cell Transplantation [PDF]

Stem Cells Translational Medicine, 2021
AbstractAllogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used in the treatment of hematological diseases. It is well known that allogeneic grafts play a key role in predicting transplantation prognosis. Hematopoietic stem cells (HSCs) are a functional part of grafts and are capable of reconstructing hematopoiesis and immunity ...
Zheng-Li Xu, Xiao-Jun Huang
openaire   +3 more sources

Allogeneic hematopoietic stem cell transplantation in Tunisia [PDF]

Bone Marrow Transplantation, 2008
In 1998, the Tunisian team of the 'Centre National de Greffe de Moelle Osseuse' initiated allogeneic hematopoietic SCT (AHSCT) in Tunisia. As of June 2007, information was collected about 299 patients with a first AHSCT and 12 additional retransplants. The median age was 19 years (range 2-49 years). The main indications were aplastic anemia (n=106, 36%)
T, Ben Othman, L, Torjemane, A, Abdelkefi, A, Lakhal, S, Ladeb, L, Ben Hamed, H, Slama, A, Ben Abdeladhim   +7 more
openaire   +2 more sources

Donation and transplantation of allogeneic hematopoietic stem cells [PDF]

Canadian Medical Association Journal, 2011
Only 30% of patients with indications for a transplant have a matched related donor; the remaining 70% seek an unrelated donor on the world’s registry. Nonwhite Canadians have a particularly low likelihood of finding a match.1,2 Appendix 1 lists common indications for transplant (available at ...
Ilana, Kopolovic, Robert, Turner
openaire   +2 more sources

Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

Journal of Hematotherapy & Stem Cell Research, 2002
Allogeneic hematopoietic stem cell transplantation (HSCT) is the most effective treatment for selected hematological malignancies. Its curative potential is largely mediated by an immune-mediated destruction of malignant cells by donor lymphocytes termed graft-versus-leukemia (GVL) effect.
Baron, Frédéric, Beguin, Yves
openaire   +3 more sources

Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

Archives of Internal Medicine, 2002
Acute complications such as veno-occlusive disease of the liver, acute and chronic graft-vs-host disease (GVHD), and infectious conditions remain major obstacles for the success of allogeneic hematopoietic stem cell transplantation (HSCT). Progress in allogeneic HSCT depends on several factors, including the adequate prevention and management of ...
Imad A, Tabbara, Kathy, Zimmerman, Connie, Morgan, Zeina, Nahleh   +3 more
openaire   +2 more sources