Results 31 to 40 of about 6,058,943 (256)

Retrospective Study of Incidence and Prognostic Significance of Eosinophilia after Allogeneic Hematopoietic Stem Cell Transplantation: Influence of Corticosteroid Therapy

Turkish Journal of Hematology, 2016
Objective: The clinical significance of eosinophilia after allogeneic hematopoietic stem cell transplantation is controversial. This study aimed to retrospectively study the impact of eosinophilia on the outcome of allogeneic hematopoietic stem cell ...
Wataru Yamamoto, Eriko Ogusa, Kenji Matsumoto, Atsuo Maruta, Yoshiaki Ishigatsubo, Heiwa Kanamori   +5 more
doaj   +1 more source

Tumor recognition by natural killer cells in acute myeloid leukemia and after hematopoietic stem cell transplantation [PDF]

, 2005
Natural killer (NK) cell-mediated cytolytic activity against tumors requires the engagement of activating NK cell receptors by the tumor-associated ligands.
Nowbakht, Pegah
core   +1 more source

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]

, 2009
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D., Chiu Sum Ying, Brian C Beard, Robert A Wu, John J Rossi, Muñoz Nina M., Nina M Muñoz, John J. Rossi, Brian C. Beard, Dorothee von Laer, Laer, Dorothee von, Grant D Trobridge, Beard Brian C., Chiu, Sum Ying, Nina M. Muñoz, Kiem, Hans-Peter, Sum Ying Chiu, Trobridge Grant D., Wu, Robert A., Hans-Peter Kiem, Kiem Hans-Peter, Beard, Brian C., Wu Robert A., von Laer Dorothee, Rossi, John J., Rossi John J., Grant D. Trobridge, Robert A. Wu, Muñoz, Nina M.   +28 more
core   +2 more sources

Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells : implications for adoptive immunotherapy after allogeneic stem cell transplantation [PDF]

, 2010
Background: Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines ...
H. Kreyenberg, Gerrit Weber, S. Kloss, Bader, Peter, Koscielniak, Ewa, A. Willasch, Selim Kuci, T. Klingebiel, E. Koscielniak, Laer, Dorothee von, Miriam Stais, Willasch, Andre Manfred, D. von Laer, Klingebiel, Thomas, Klöß, Stephan, Stais, Miriam, Kuçi, Selim, Peter Bader, Eva Rettinger, Thomas Klingebiel, B. Voss, Z. Kuci, Kreyenberg, Hermann, Stephan Klöss, G. Weber, Dorothee Von Laer, E. Rettinger, Zyrafete Kuci, Kuçi, Zyrafete, Rettinger, Eva, Bernhard Voss, M. Stais, P. Bader, Hermann Kreyenberg, Weber, Gerrit, Voß, Bernhard, Ewa Koscielniak, Andre Willasch, S. Kuci   +38 more
core   +1 more source

Prospective study of hepatitis B virus reactivation in patients with hematological malignancies

Annals of Hepatology, 2015
Background and aim. The best strategy for managing patients with resolved hepatitis B virus infection (HBsAg negative, anti-HBc antibodies positive with or without anti-HBs antibodies) and hematological malignancies under immunosuppressive therapies has ...
Maurizio Pompili, Maria Basso, Stefan Hohaus, Giulia Bosco, Lorenzo Nosotti, Mariella D’Andrea, Susanna Fenu, Antonio Grieco, Luca Laurenti, Concetta Mirisola, Livio Pagano, Gian Ludovico Rapaccini, Simona Sica, Sergio Storti, Raffaele Landolfi   +14 more
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Therapeutic choices in patients with Ph-Positive chronic myelogenous leukemia in Mexico in the era of tyrosine kinase inhibitors: stem cell transplantation or tyrosine kinase inhibitors? Fifteen years later

Revista de Investigación Clínica
Background: Chronic myelogenous leukemia is a neoplastic proliferation of the granulocytic series. In Mexico, chronic myelogenous leukemia accounts for approximately 10% of all leukemias.
Max Robles-Nasta, Daniela Sánchez-Bonilla, Moises M. Gallardo-Pérez, Edgar J. Hernández-Flores, Merittzel A. Montes-Robles, María de L. Pastelín-Martínez, Juan C. Olivares-Gazca, Guillermo J. Ruiz-Delgado, Guillermo J. Ruiz-Argüelles   +8 more
doaj   +1 more source

Pralatrexate as a bridge to allogeneic hematopoietic stem cell transplantation in a patient with advanced-stage extranodal nasal-type natural killer/T cell lymphoma refractory to first-line chemotherapy: a case report

Journal of Medical Case Reports, 2020
Background Extranodal natural killer/T cell lymphoma, nasal type, is one of the more common subtypes of mature T cell lymphoma, especially in the Far East Asian population.
Yao-Chung Liu, Ting-An Lin, Hao-Yuan Wang, Po-Shen Ko, Chia-Jen Liu, Liang-Tsai Hsiao, Sheng-Hsuan Chien, Jyh-Pyng Gau   +7 more
doaj   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source