Female genital tract chronic graft-versus-host disease: A narrative review
Graft-versus-host disease is one of the main causes of morbidity and mortality in patients submitted to hematopoietic stem cell transplantation. This study reviewed the prevalence of lower female genital tract graft-versus-host disease following ...
Andréa Maria Novaes Machado +5 more
doaj +1 more source
Allogeneic hematopoietic stem cell transplantation in mycosis fungoides [PDF]
Mycosis Fungoides is typically an indolent disease in early stages. However, approximately 30% of patients have advanced staged disease at presentation and 20% will develop it at some time. These patients have a poorer prognosis with a median survival of
Angelo Atalla +3 more
doaj +1 more source
Perforin gene transfer into hematopoietic stem cells improves immune dysregulation in murine models of perforin deficiency [PDF]
Defects in perforin lead to the failure of T and NK cell cytotoxicity, hypercytokinemia, and the immune dysregulatory condition known as familial hemophagocytic lymphohistiocytosis (FHL).
Montiel-Equihua, CA +13 more
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Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Kolb, Hans-Jochem +8 more
core +1 more source
A Comparison of Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Myeloblastic Leukemia [PDF]
Introduction: Acute Myelogenous Leukemia (AML) is a clonal malignant disease of hematopoietic tissue. The early use of Hematopoietic Stem Cell Transplantation (HSCT) for AML was for patients with advanced stages of disease, usually while in relapse, in
Ardeshir Ghavamzadeh +4 more
doaj +1 more source
Allogeneic hematopoietic stem cell transplantation for myelofibrosis
Primary myelofibrosis (PMF) or myelofibrosis secondary to polycythemia vera (PV-MF) or essential thrombocythemia (ET-MF) can be cured only by means of allogeneic hematopoietic stem cell transplantation (HSCT).[1][1] However, the age of the patient, the number of circulating blasts ...
openaire +3 more sources
Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Meyer, Claus +23 more
core +1 more source
Plasticity after allogeneic hematopoietic stem cell transplantation [PDF]
Abstract The postulated almost unlimited potential of transplanted hematopoietic stem cells (HSCs) to transdifferentiate into cell types that do not belong to the hematopoietic system denotes a complete paradigm shift of the hierarchical hemopoietic tree.
Rovó, A., Gratwohl, A.
openaire +4 more sources
Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Yumi Matsuzaki +12 more
core
Hematopoietic stem cell transplantation in Iran: 1991 to 2008
Since 1991,2042 first hematopoietic stem cell transplants (HSCT) have been performed at the Hematology- Oncology and stem cell Transplantation Research center at Tehran university of Medical sciences.
Ardeshir Ghavamzadeh +8 more
doaj +1 more source

