Results 61 to 70 of about 61,607 (214)

Epigenetic therapy in allogeneic hematopoietic stem cell transplantation [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2013
DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decitabine have anti-tumor activity against a broad range ...
Bashir, Qaiser, William, Basem Magdy, Garcia-Manero, Guillermo, Lima, Marcos de   +3 more
openaire   +5 more sources

Immunogenicity of allogeneic mouse mesenchymal stem cells (MSC) [PDF]

, 2012
Adult mesenchymal stem cells (MSC) are multipotential cells which can differentiate into various cell types thus giving them utility in tissue engineering regenerative medicine and cell-based therapies.
Mukonoweshuro, Blessing
core  

Diffuse alveolar hemorrhage is most often fatal and is affected by graft source, conditioning regimen toxicity, and engraftment kinetics

Haematologica, 2018
Diffuse alveolar hemorrhage after hematopoietic stem cell transplantation is a frequently fatal complication with no standard therapy. Although significant changes in supportive and intensive care measures for patients undergoing hematopoietic stem cell ...
Fatma Keklik, Ezzideen Barjes Alrawi, Qing Cao, Nelli Bejanyan, Armin Rashidi, Aleksandr Lazaryan, Patrick Arndt, Erhan H. Dincer, Veronika Bachanova, Erica D. Warlick, Margaret L. MacMillan, Mukta Arora, Jeffrey Miller, Claudio G Brunstein, Daniel J. Weisdorf, Celalettin Ustun   +15 more
doaj   +1 more source

Experience of BK Virus in Allogenic and Autologous Bone Marrow Transplantation:

Mediterranean Journal of Hematology and Infectious Diseases, 2014
The BK virus is a member of the polyomavirus family. When the immune system is compromised, as in patients undergoing chemotherapy after hematopoietic stem cell and solid organ transplantation, the virus is reactivated leading to haemorrhagic cystitis ...
Ilhami BERBER, Mehmet Ali ERKURT, Emin KAYA, Irfan KUKU, Mustafa KOROGLU, Ilknur NIZAM   +5 more
doaj  

Assessing the impact of ABO incompatibility on major allogeneic hematopoietic stem cell transplant outcomes: a prospective, single-center, cohort study

Hematology, Transfusion and Cell Therapy, 2019
Background: ABO blood group incompatibility between donor and recipient is associated with a number of immunohematological complications, but is not considered a major contraindication to allogeneic hematopoietic stem cell transplantation.
José Alfreu Soares Júnior, Glaucia Helena Martinho, Antonio Vaz de Macedo, Marisa Ribeiro Verçosa, Vandack Nobre, Gustavo Machado Teixeira   +5 more
doaj   +1 more source

Pulmonary tuberculosis in allogeneic hematopoietic stem cell transplantation [PDF]

Bone Marrow Transplantation, 2001
Pulmonary tuberculosis (TB) is an endemic infectious disease in Taiwan. A retrospective study was conducted to define clinical manifestations and outcomes of patients with pulmonary TB among hematopoietic stem cell transplantation (HSCT) recipients. We identified eight out of 350 HSCT recipients as having pulmonary TB over a 6-year period. The relative
S C, Ku, J L, Tang, P R, Hsueh, K T, Luh, C J, Yu, P C, Yang   +5 more
openaire   +2 more sources

Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse

, 2012
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Meyer, Claus, Carola Tietze-Bürger, Claus Meyer, Igor Blau, Burmeister, Thomas, Molkentin, Mara, Thomas Burmeister, Mara Molkentin, Nils Lachmann, Uharek, Lutz, Rolf Marschalek, Tietze-Bürger, Carola, Friedrichs, Birte, Blau, Igor Wolfgang, Jörg Beyer, Marschalek, Rolf, Schwartz, Stefan, Lutz Uharek, Beyer, Jörg, Stefan Schwartz, Gunnar Lohm, Birte Friedrichs, Lachmann, Nils, Lohm, Gunnar   +23 more
core   +1 more source

Breakdown of thymic tolerance - an etiologic link between acute and chronic graft-versus-host disease [PDF]

, 2014
Allogeneic haematopoietic stem cell transplantation (HSCT) is the standard therapy for many disorders of the haematological system. Its use is limited by the major complication acute graft-versus-host disease (GVHD). Development of acute GVHD predisposes
Dertschnig, Simone
core   +1 more source

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection

, 2009
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D., Chiu Sum Ying, Brian C Beard, Robert A Wu, John J Rossi, Muñoz Nina M., Nina M Muñoz, John J. Rossi, Brian C. Beard, Dorothee von Laer, Laer, Dorothee von, Grant D Trobridge, Beard Brian C., Chiu, Sum Ying, Nina M. Muñoz, Kiem, Hans-Peter, Sum Ying Chiu, Trobridge Grant D., Wu, Robert A., Hans-Peter Kiem, Kiem Hans-Peter, Beard, Brian C., Wu Robert A., von Laer Dorothee, Rossi, John J., Rossi John J., Grant D. Trobridge, Robert A. Wu, Muñoz, Nina M.   +28 more
core   +1 more source

Longitudinal assessment of oral intake adequacy and nutrition-impacted symptoms in patients undergoing allogeneic hematopoietic stem cell transplantation

Frontiers in Nutrition
AimsThis study aims to longitudinally assess the adequacy of oral intake and burden of nutrition-impacted symptoms (NIS) and identify modifiable factors associated with oral intake adequacy in allogeneic hematopoietic stem cell transplantation patients ...
Liyuan Qin, Rui Li, Jiaqi Wu, Yang He
doaj   +1 more source