Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D. +28 more
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Objective:This study aimed to describe and compare the nutritional status of adult patients submitted to allogeneic hematopoietic stem cell transplantation at two different time points (admission and discharge).Methods:A retrospective, descriptive and ...
Érika Elias Ferreira +4 more
doaj +1 more source
Diffuse alveolar hemorrhage after hematopoietic stem cell transplantation is a frequently fatal complication with no standard therapy. Although significant changes in supportive and intensive care measures for patients undergoing hematopoietic stem cell ...
Fatma Keklik +15 more
doaj +1 more source
Cytotoxic capacity of IL-15-stimulated cytokine-induced killer cells against human acute myeloid leukemia and rhabdomyosarcoma in humanized preclinical mouse models [PDF]
Allogeneic stem cell transplantation (allo-SCT) has become an important treatment modality for patients with high-risk acute myeloid leukemia (AML) and is also under investigation for soft tissue sarcomas.
Wels, Winfried +35 more
core +1 more source
Experience of BK Virus in Allogenic and Autologous Bone Marrow Transplantation:
The BK virus is a member of the polyomavirus family. When the immune system is compromised, as in patients undergoing chemotherapy after hematopoietic stem cell and solid organ transplantation, the virus is reactivated leading to haemorrhagic cystitis ...
Ilhami BERBER +5 more
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Background: ABO blood group incompatibility between donor and recipient is associated with a number of immunohematological complications, but is not considered a major contraindication to allogeneic hematopoietic stem cell transplantation.
José Alfreu Soares Júnior +5 more
doaj +1 more source
Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers [PDF]
Stem cell transplantation is used widely in the management of a range of diseases of the hemopoietic system. Patients are immunosuppressed profoundly in the early posttransplant period, and reactivation of cytomegalovirus (CMV) remains a significant ...
Premini Mahendra +60 more
core +1 more source
Disorders of endocrine, reproductive and skeletal systems following allogeneic or autologous stem cell transplantation for hematological malignancies in adults [PDF]
Introduzione Il progressivo aumento del numero dei pazienti sopravviventi a lungo termine dopo la guarigione da malignità emopoietiche ha portato a focalizzare l’attenzione sulle complicanze precoci e tardive delle malattie e dei loro trattamenti.
Tauchmanova, Libuse
core +1 more source
Identification of the niche and phenotype of the first human hematopoietic stem cells [PDF]
In various vertebrate species, the dorsal aorta (Ao) is the site of specification of adult hematopoietic stem cells (HSCs). It has been observed that the upregulation of essential hematopoietic transcription factors and the formation of specific intra ...
Stanislav Rybtsov +11 more
core +1 more source
Hematopoietic stem cell transplantation
Eleftheria Hatzimichael1, Mark Tuthill21Department of Haematology, Medical School of Ioannina, University of Ioannina, Ioannina, Greece; 2Department of Medical Oncology, Hammersmith Hospital, Imperial College National Health Service Trust, London ...
Eleftheria Hatzimichael, Mark Tuthill
doaj

