Results 91 to 100 of about 415,260 (411)

Engineered Peptides‐Based Hybrid‐Nested Microneedle Effectively Treat Biofilm‐Infected Diabetic Wounds

Advanced Functional Materials, EarlyView.
A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi, S. M. Shatil Shahriar, Yiran Tian, Farzad Hayati, Yajuan Su, Feng Zhang, Navatha Shree Sharma, Guangshun Wang, Shannon L. Wong, Zheng Yan, Guoliang Huang, Jingwei Xie   +11 more
wiley   +1 more source

Acellular allogeneic nerve grafting combined with bone marrow mesenchymal stem cell transplantation for the repair of long-segment sciatic nerve defects: biomechanics and validation of mathematical models

Neural Regeneration Research, 2016
We hypothesized that a chemically extracted acellular allogeneic nerve graft used in combination with bone marrow mesenchymal stem cell transplantation would be an effective treatment for long-segment sciatic nerve defects.
Ya-jun Li, Bao-lin Zhao, Hao-ze Lv, Zhi-gang Qin, Min Luo   +4 more
doaj   +1 more source

Epidemiology and potential preventative measures for viral infections in children with malignancy and those undergoing hematopoietic cell transplantation. [PDF]

, 2012
In pediatric patients with malignancy and those receiving hematopoietic stem cell transplants, bacterial and fungal infections have been the focus of fever and neutropenia episodes for decades.
Alexander, Sarah, Dvorak, Christopher C, Fisher, Brian T, Sung, Lillian, Zaoutis, Theoklis E, Zerr, Danielle M   +5 more
core   +1 more source

Allogeneic Stem Cell Transplantation with CD34+ Cell Selection

Clinical Hematology International, 2019
The success of allogeneic stem cell transplant is hampered by the development of acute and chronic graft-versus-host disease (GvHD) which has direct impact on treatment-related mortality and morbidity. As a result, T cell depletion through positive selection of CD34+ cells has emerged as a promising strategy to reduce acute and chronic GvHD in these ...
Pere Barba, Miguel-Angel Perales, Elisa Roldán   +2 more
openaire   +4 more sources

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

Therapeutic choices in patients with Ph-Positive chronic myelogenous leukemia in Mexico in the era of tyrosine kinase inhibitors: stem cell transplantation or tyrosine kinase inhibitors? Fifteen years later

Revista de Investigación Clínica
Background: Chronic myelogenous leukemia is a neoplastic proliferation of the granulocytic series. In Mexico, chronic myelogenous leukemia accounts for approximately 10% of all leukemias.
Max Robles-Nasta, Daniela Sánchez-Bonilla, Moises M. Gallardo-Pérez, Edgar J. Hernández-Flores, Merittzel A. Montes-Robles, María de L. Pastelín-Martínez, Juan C. Olivares-Gazca, Guillermo J. Ruiz-Delgado, Guillermo J. Ruiz-Argüelles   +8 more
doaj   +1 more source

Bayesian inference and model choice in a hidden stochastic two-compartment model of hematopoietic stem cell fate decisions [PDF]

Annals of Applied Statistics 2009, Vol. 3, No. 4, 1695-1709, 2010
Despite rapid advances in experimental cell biology, the in vivo behavior of hematopoietic stem cells (HSC) cannot be directly observed and measured. Previously we modeled feline hematopoiesis using a two-compartment hidden Markov process that had birth and emigration events in the first compartment.
arxiv   +1 more source

Stem cell sources for regenerative medicine: the immunological point of view [PDF]

, 2018
Stem cell transplantation consists in the introduction of stem cells or derived products in a diseased organism. Because of the differentiation properties of stem cells, the goal is to replace damaged cells or tissues.
Krause, Karl-Heinz, Preynat-Seauve, Olivier   +1 more
core  

Alemtuzumab in allogeneic hematopoetic stem cell transplantation [PDF]

Expert Opinion on Biological Therapy, 2011
With the use of reduced-intensity conditioning (RIC), early toxicity of allogeneic stem cell transplantation (SCT) has been much reduced. Graft-versus-host disease (GvHD) causes morbidities and mortality. Alemtuzumab is a mAb directed against CD52. When administered prior to transplant, it leads to T-cell depletion.
Xavier Poiré, Koen van Besien
openaire   +3 more sources

Materials Advances in Devices for Heart Disease Interventions

Advanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra, Lauryn Srethbhakdi, James Davies, Chi Cong Nguyen, Phuoc Thien Phan, Zachary Och, Aditya Ashok, Khoon S. Lim, Hoang‐Phuong Phan, Thanh Nho Do, Nigel H. Lovell, Jelena Rnjak‐Kovacina   +11 more
wiley   +1 more source