Results 171 to 180 of about 72,842 (263)

Comparative proteome analyses of human natural killer cells from patients after allogeneic stem cell transplantation and healthy individuals challenged with <i>Aspergillus fumigatus</i>. [PDF]

Microlife
Springer J, Drobny M, Heilig L, Kraus S, Kniemeyer O, Krüger T, Olischer C, Bussemer L, Panagiotou G, Brakhage AA, Einsele H, Schäuble S, Löffler J.   +12 more
europepmc   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Letermovir Prophylaxis for Cytomegalovirus Infection in Adult Allogeneic Stem Cell Transplantation: A Retrospective Analysis From a Lower-Middle-Income Country. [PDF]

Cureus
Rastogi N, Bhayana S, Chahal K, Kumar NM, Swaminathan A, Panda A, Bharat S, Chizaram O, Nathany S, Paul A, Agrawal R, Dua V, Bhargava R.   +12 more
europepmc   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source

Impact of expanding allogeneic stem cell transplantation on survival in acute myeloid leukemia: a population-based study. [PDF]

Blood Cancer J
Salter B, Garcia-Horton A, Walker I, Leber B, Lepic K, Mian H, Gayowsky A, Pond GR, Seow H, Berg T.   +9 more
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Real World Study on the Best CPX-351 Treatment Duration and Timing for Allogeneic Stem Cell Transplantation. [PDF]

Am J Hematol
Guolo F, Fianchi L, Martelli MP, Lussana F, Grimaldi F, Pilo F, Rondoni M, Filì C, Minetto P, Capelli D, Chiusolo P, Breccia M, Mastaglio S, Bernardi M, Bocchia M, Fumagalli M, Galimberti S, Mancini V, Piccioni AL, Maurillo L, Fracchiolla NS, Palmieri R, Vetro C, Papayannidis C, Brunetti L, Sperotto A, Gigli F, Zappasodi P, Mulé A, Patti C, Borlenghi E, Dargenio M, Lessi F, Cerrano M, Cilloni D, Isidori A, Lunghi M, Alati C, Gurrieri C, Riva C, Marconi G, Lotesoriere I, Gatani S, Scattolin AM, Caizzi M, Perrone S, Billio A, Gherlinzoni F, Mannelli F, Gottardi M, Cairoli R, Candoni A, Ferrara F, Pagano L, Lemoli RM, Venditti A, Todisco E.   +56 more
europepmc   +1 more source

Exportin 1 Inhibitor Combined With Venetoclax Induces Apoptosis in Myelodysplastic Syndrome by Mitochondria‐Induced Apoptosis Pathway

Journal of Clinical Laboratory Analysis, EarlyView.
Inhibition of XPO1 is a promising modality in the treatment of MDS, especially when combined with Venetoclax, which activates mitochondria‐mediated apoptosis and could be a potential target for MDS therapy. ABSTRACT Background Myelodysplastic syndromes (MDS) are clonal hematopoietic malignancies that pose a serious health threat.
Xiaohan Liu, Lei Huang, Junzhu Wang, Yixuan Guo, Hongli Shen, Xianghong Zhao, Lanzhu Yue, Zhaoyun Liu, Rong Fu   +8 more
wiley   +1 more source

Mucosal calprotectin is associated with severity of aGI-GVHD and poor outcomes after allogeneic stem cell transplantation.

Blood
Gurer Kluge EE, Meedt E, Feicht J, Cao K, Hiergeist A, Mamilos A, Hirsch D, Hoepting M, Kattner AS, Matos C, Bülow S, Thiele Orberg E, Beckhove P, Kandulski A, Evert M, Hildner K, Kreutz M, Edinger M, Wolff D, Herr W, Poeck H, Gessner A, Weber D, Kehr B, Holler E, Ghimire S.   +25 more
europepmc   +1 more source

Association between pre-transplant CONUT score and pneumonia risk after allogeneic stem cell transplantation in acute leukemia. [PDF]

BMC Pulm Med
Yenibertiz D, Akkurt ES, Düvenci̇ Bi̇rben Ö, Darçin T, Türk Ü, Dal MS.   +5 more
europepmc   +1 more source