Results 201 to 210 of about 415,260 (411)

Pleural CD14+ monocytes/macrophages of healthy adolescents show a high expression of metallothionein family genes

open access: yesEuropean Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
Modern surgical (technical) possibilities enable pleural macrophage isolation and analyses regardless the person`s age. Transcriptome profiling of macrophages from healthy or sick individuals revealed that these cells express high levels of metallothioneins, metal‐binding proteins that are involved in heavy metal detoxification, antioxidative defense ...
Nagoud Schukfeh   +11 more
wiley   +1 more source

Multiple imputation of missing covariates when using the Fine-Gray model [PDF]

open access: yesarXiv
The Fine-Gray model for the subdistribution hazard is commonly used for estimating associations between covariates and competing risks outcomes. When there are missing values in the covariates included in a given model, researchers may wish to multiply impute them.
arxiv  

Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study

open access: yesEuropean Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
The effect of habitual Western diet and salt‐reduced diet on the levels of systemic blood cytokines was analyzed in a placebo‐controlled nutritional intervention study. The results showed that reduced salt intake did not alter the concentrations of any of the analyzed 34 cytokines in blood.
Teemu Niiranen   +4 more
wiley   +1 more source

Stem Cells: The Good, the Bad and the Ugly [PDF]

open access: yesarXiv, 2016
Cancer stem cells are controlled by developmental networks that are often topologically indistinguishable from normal, healthy stem cells. The question is why cancer stem cells can be both phenotypically distinct and have morphological effects so different from normal stem cells.
arxiv  

Physically “fit” for allogeneic stem cell transplant? [PDF]

open access: yesBone Marrow Transplantation, 2021
Reena V. Jayani, Rebecca L. Olin
openaire   +2 more sources

Replicator Dynamics of of Cancer Stem Cell; Selection in the Presence of Differentiation and Plasticity [PDF]

open access: yesarXiv, 2014
Stem cells have the potential to produce lineages of non-stem cell populations (differentiated cells) via a ubiquitous hierarchal division scheme. Differentiation of a stem cell into (partially) differentiated cells can happen either symmetrically or asymmetrically. The selection dynamics of a mutant cancer stem cell should be investigated in the light
arxiv  

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

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