Results 51 to 60 of about 131,145 (309)

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Giant Cell Tumor of The Proximal Phalanx of The Index Finger of The Hand: A Rare Case Report

Journal Orthopaedi and Traumatology Surabaya, 2022
Background: Giant cell tumor (GCT) of bone is a relatively common type of benign tumor involving the epiphyseal region of tubular bones, but GCT rarely occurs at hand (1–4% of all GCT).
Mouli Edward, Ferdiansyah Mahyudin, Muhammad Hardian Basuki, Yunus Basrewan, Caesar Haryo Bimoseno   +4 more
doaj   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

A small molecule beta2 integrin agonist improves chronic kidney allograft survival by reducing leukocyte recruitment and accompanying vasculopathy

Frontiers in Medicine, 2014
Kidney allograft rejection is associated with infiltration of inflammatory CD11b+ leukocytes. A CD11b agonist leukadherin-1 (LA1) increases leukocyte adhesion, preventing transmigration and tissue recruitment in vivo. Here we test the extent to which LA1
Vineet eGupta
doaj   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Lung Allograft Epithelium DNA Methylation Age Is Associated With Graft Chronologic Age and Primary Graft Dysfunction

Frontiers in Immunology, 2021
Advanced donor age is a risk factor for poor survival following lung transplantation. However, recent work identifying epigenetic determinants of aging has shown that biologic age may not always reflect chronologic age and that stressors can accelerate ...
Daniel T. Dugger, Daniel R. Calabrese, Daniel R. Calabrese, Ying Gao, Fred Deiter, Tasha Tsao, Julia Maheshwari, Steven R. Hays, Lorriana Leard, Mary Ellen Kleinhenz, Rupal Shah, Jeff Golden, Jasleen Kukreja, Erin D. Gordon, Jonathan P. Singer, John R. Greenland, John R. Greenland   +16 more
doaj   +1 more source

Effect of the shipment of cadaveric renal allografts on allograft survival [PDF]

Nephrology Dialysis Transplantation, 2007
Since 1996, the allocation of grafts in France has been based on a hierarchical three-level system: national, regional and local. The objective of this study was to determine whether the shipment of cadaveric kidneys according to these new exchange rules affects allograft outcome in the Eastern region of France.This retrospective study analysed all ...
Kessler, Michèle, Virion, Jean-Marc, Hachicha, Mourad, Moulin, Bruno, Toupance, Olivier, Rebibou, Jean-Michel, Guillemin, Francis   +6 more
openaire   +4 more sources

Studies of clinically applicable human tolerogenic dendritic cells and PD-L2 genetic modification of human islet allograft to promote graft tolerance. [PDF]

, 2011
Islet transplantation is a developing therapy for type 1 diabetic patients (T1D), which has been limited by problems associated with hypoxia, poor revascularisation and allograft rejection.
Rojas-Canales, Darling
core  

A biomechanical cadaveric study comparing superior capsule reconstruction using fascia lata allograft with human dermal allograft for irreparable rotator cuff tear.

, 2017
BACKGROUND Biomechanical and clinical success of the superior capsule reconstruction (SCR) using fascia lata (FL) grafts has been reported.
Bui, Christopher N H, Itami, Yasuo, Masashi Neo, Neo, Masashi, Lee, Thay Q, Akeda, Masaki, Alexander B. Peterson, Künzler, Michael, Michael Kuenzler, Orr Limpisvasti, Matthew A. Cavagnaro, Thay Q. Lee, Mihata, Teruhisa, Yasuo Itami, McGarry, Michelle H, Michelle H. McGarry, Peterson, Alexander B, Masaki Akeda, Christopher N.H. Bui, Limpisvasti, Orr, Teruhisa Mihata, Cavagnaro, Matthew A   +21 more
core   +1 more source

Development of a multivariate prediction model for early-onset bronchiolitis obliterans syndrome and restrictive allograft syndrome in lung transplantation [PDF]

, 2017
International audienceBackground: Chronic lung allograft dysfunction and its main phenotypes, bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), are major causes of mortality after lung transplantation (LT).
Martine L. Reynaud-Gaubert, Sage, E, Benden, Christian, Pierre J. Royer, Aubert, J.D., Soccal, P.M., Roux, A., Chung, Kian, Fan, Knoop, C., Gasche-Soccal, Paola Marina Alessandra, Jean P. Antonietti, Nicod, L., Aubert, John D, null null, Dahan, Marcel, Mussot, Sacha, Kessler, R., Gomez, C, Roux, Antoine, Fritz, Andreas, Mornex, J.F., Royer, PJ, Tissot, A., Antonietti, Jean P., Gomez, Carine, Adrien Tissot, Johanna Claustre, Botturi, K, Antonietti, Jean P, Gomez, C., Christian Benden, Royer, P.J., Pison, Christophe, Guillemain, R, Antoine Roux, Kessler, R, Carine Gomez, Reynaud-Gaubert, ML, Roux, A, Mal, H., Botturi, Karine, Hillerdal, Gunnar,, Sacha Mussot, The SysCLAD Consortium, Claire Dromer, Reynaud-Gaubert, Martine L., Fritz, A., Sage, E., Mal, Herve, Mornex, Jean-Francois, Wewers, Mark, Antonietti, J.P., Chung, Kian,, Angela Koutsokera, Tissot, A, Dahan, M., Benden, C, Magnan, A, Antoine Magnan, Reynaud Gaubert, Martine L., Dahan, M, Mornex, J-F, Kessler, Romain, Guillemain, R., Dromer, Claire, Benden, C., Romain Guillemain, Koutsokera, A, Botturi, K., Dromer, C., Antonietti, J.-Ph, John D. Aubert, Magnan, Antoine, Laurent P. Nicod, Aubert, John D., Pison, C., Aubert, JD, Tissot, Adrien, Reynaud-Gaubert, M.L., Sage, Edouard, Karine Botturi, Magnan, A., Systems prediction of Chronic Lung Allograft Dysfunction, Hillerdal, Gunnar, N, Marcel Dahan, Fritz, A, Jean-François Mornex, Claustre, J., Nicod, Laurent P, Hervé Mal, Romain Kessler, Royer, Pierre J, Soccal, PM, Nicod, L.P., Edouard Sage, Guillemain, Romain, Claustre, J, Royer, Pierre J., Reynaud-Gaubert, Martine L, Koutsokera, A., Paola M. Soccal, Christiane Knoop, Claustre, Johanna, Mussot, S., Soccal, Paola M., Mal, H, Koutsokera, Angela, Andreas Fritz, Knoop, Christiane, Christophe Pison, Nicod, Laurent P.   +110 more
core   +1 more source