Results 61 to 70 of about 143,389 (254)

Proteomics in Kidney Allograft Transplantation—Application of Molecular Pathway Analysis for Kidney Allograft Disease Phenotypic Biomarker Selection

, 2019
International audienceThere is a need for accurate, robust, non‐invasive methods to provide early diagnosis of graft lesions after kidney transplantation.
Olagne, Jérôme, Sophie Caillard, Wilfried Gwinner, Colombat, Magali, Mullen, William, Stanislas Faguer, William Mullen, Jochen Metzger, Caillard, Sophie, Gwinner, Wilfried, Holger Husi, Faguer, Stanislas, David Marx, Husi, Holger, Jérôme Olagne, Metzger, Jochen, Iwona Belczacka, Magali Colombat, Marx, David, Belczacka, Iwona   +19 more
core   +1 more source

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Advanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov   +9 more
wiley   +1 more source

Comparative evaluation of free gingival graft and AlloDerm® in enhancing the width of attached gingival: A clinical study

Contemporary Clinical Dentistry, 2015
Background: The presence of an adequate width of keratinized tissue is important to maintain a healthy dentogingival junction. In case of inadequate width of attached gingiva, the gingival augmentation procedure has been performed classically using the ...
Chitra Agarwal, A B Tarun Kumar, Dhoom Singh Mehta   +2 more
doaj   +1 more source

Overcoming skin rejection in composite tissue allotransplantation [PDF]

, 2008
The application of composite tissue techniques is constrained by the susceptibility of skin to rejection. The aim of this thesis is to improve our understanding of skin rejection and find ways to avoid it, in order to enable expansion of the ...
Horner, B., Horner, R.
core  

CT based classification of long spinal allograft fusion

, 2007
Anterior column reconstruction of the thoracolumbar spine by structural allograft has an increased potential for biological fusion when compared to synthetic reconstructive options.
Williams, Richard, P. J. Thorpe, B. G. Goss, Thorpe, Paul L., Tan, G., Goss, Benjamin G., R. P. Williams, G. H. Tan   +7 more
core   +1 more source

Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target

Advanced Science, EarlyView.
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen, Pingmei Huang, Ruizhi Tao, Fenfen Ji, Qinyao Wei, Lok Hin Ko, Lianxin Zhou, Huarong Chen, Alvin Cheung, Wei Kang, Ko Fai To, Jun Yu, Chi Chun Wong   +12 more
wiley   +1 more source

The evaluation of chip freeze-dried cancellous bone allograft of local products usage as a scaffold in completing small defects on long bone [PDF]

, 2020
Background: Bone graft as a therapeutic modality for bone defects reconstruction has been widely applied. Bone autograft is the optimum comparative standard for each substitute material, but can still cause complications and limited availability.
Ronald Vinantius Munthe, Tri Wahyu Martanto, Aries Rakhmat Hidayat, Heri Suroto, Sulis Bayusentono, Ferdiansyah Mahyudin   +5 more
core   +1 more source

Allograft Survival with Calcineurin Inhibitors [PDF]

, 2008
The immunosuppressive drugs cyclosporine A (CsA) and tacrolimus (FK506), also called calcineurin inhibitors, have truly revolutionized allograft transplantation.
Esther Voegelin, Jones, Neil F., Neil F. Jones, Vögelin, Esther   +3 more
core   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source