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Rate of RhD‐alloimmunization after the transfusion of multiple RhD‐positive primary red blood cell‐containing products

Transfusion, 2021
Early transfusion reduces mortality in bleeding patients. In this setting, RhD‐positive blood products might be transfused. This study determined the association between the RhD‐alloimmunization rate and the number of RhD‐positive products transfused.
M. Yazer   +3 more
semanticscholar   +1 more source

Transfusion requirements and alloimmunization to red blood cell antigens in orthotopic liver transplantation

Vox Sanguinis, 2021
Orthotopic liver transplantation (OLT) has been associated with high blood transfusion requirements. We evaluated the transfusion needs and frequency of alloimmunization to RBC antigens among OLT recipients pre‐ and post‐transplantation.
A. Uzuni   +7 more
semanticscholar   +1 more source

Multidisciplinary management of anti‐PP1Pk or anti‐P alloimmunization during pregnancy: A new case with anti‐P and a literature review

Transfusion, 2021
Red blood cell alloimmunization is the first cause of fetal and neonatal anemia. Alloimmunizations with anti‐PP1Pk or anti‐P can cause recurrent miscarriages and hemolytic disease of the fetus and newborn in the 2nd and 3rd trimesters of pregnancy.
M. Lépine   +12 more
semanticscholar   +1 more source

Alloimmune Thrombocytopenia

Clinical Obstetrics and Gynecology, 1999
For the fetuses who are at risk for antenatal or postnatal sequelae from AIT, prevention and treatment are now possible. This requires the attention of the obstetrician to factors in the patient's history and early referral to a center experienced in the diagnosis and management of fetal AIT.
D W, Skupski, J B, Bussel
openaire   +2 more sources

Non‐transfusion dependent thalassemia is independently associated with higher alloimmunization risk than transfusion dependent thalassemia and would benefit the most from extended red cell antigen‐matching

Transfusion, 2021
Alloimmunization prevalence is conventionally used to identify RBCs alloimmunization risk factors among thalassemia patients, but it may be confounded by differences in transfusion exposure especially between non‐transfusion dependent thalassemia (NTDT ...
Ai Leen Ang, C. Y. Lim, W. Ng, J. Lam
semanticscholar   +1 more source

Fetal Alloimmune Thrombocytopenia

Obstetrical & Gynecological Survey, 1997
Alloimmune thrombocytopenia is a serious fetal disorder resulting from platelet-antigen incompatibility between the mother and fetus. The diagnosis is usually made after the discovery of unexpected neonatal thrombocytopenia. Approximately 10 to 20 percent of affected fetuses have intracranial hemorrhages, one quarter to one half of which occur in utero.
James B. Bussel   +3 more
openaire   +4 more sources

The alloimmune thrombocytopenic syndromes

Transfusion Medicine Reviews, 1997
We have summarized five thrombocytopenic syndromes caused by platelet-reactive alloantibodies. Increased awareness of these five syndromes, together with the greater availability of highly-specialized laboratory methods to detect and to characterize platelet-reactive alloantibodies, will lead to their more frequent diagnosis.
James W. Smith, Theodore E. Warkentin
openaire   +2 more sources

Red cell alloimmunization: A 2020 update

Prenatal Diagnosis, 2020
Management of maternal red cell alloimmunization has been revolutionized over the last 60 years. Advances in the prevention, screening, diagnosis, and treatment of alloimmune‐induced fetal anemia make this condition an exemplar for contemporary practice ...
J. Castleman, M. Kilby
semanticscholar   +1 more source

Impact of red blood cell alloimmunization on fetal and neonatal outcomes: A single center cohort study

Transfusion, 2020
Alloimmunization can impact both the fetus and neonate. Study objectives: (a) calculate the incidence of clinically significant RBC isoimmunization during pregnancy, (b) review maternal management and neonatal outcomes, (c) assess the value of prenatal ...
L. Lieberman   +7 more
semanticscholar   +1 more source

Alloimmunity in pancreas transplantation

Current Opinion in Organ Transplantation, 2020
Purpose of reviewDespite significant improvement in pancreas allograft survival, rejection continues to be a major clinical problem. This review will focus on emerging literature related to the impact of pretransplant and de-novo DSA (dnDSA) in pancreas transplant recipients, and the diagnosis and treatment of T-cell-medicated rejection (TCMR) and ...
Talal Al-Qaoud   +6 more
openaire   +3 more sources

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