Results 251 to 260 of about 16,837 (286)
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Alloimmune Thrombocytopenias

Journal of Pediatric Hematology/Oncology, 2003
Alloimmunization against platelet antigens may take place during pregnancy and following transfusion or transplantation. The resulting antibodies bind to the target platelet antigens and may lead to a rapid sequestration of incompatible platelets.
openaire   +2 more sources

Alloimmune Neonatal Neutropenia

Journal of Pediatric Hematology/Oncology, 1991
In three neonates, the diagnosis of anti-NA1 alloimmune neutropenia related to maternal immunization against fetal polymorphonuclear leukocytes (PMN) antigens was achieved by serum antibody screening and PMN phenotyping. All the children were small for date and exhibited bacterial infection within days 2-13. Neutropenia persisted until days 20-50. High-
P Farrokhi   +6 more
openaire   +3 more sources

Neonatal Alloimmune Amegakaryocytosis

Vox Sanguinis, 1988
Abstract. A case of neonatal alloimmune thrombocytopenia with amegakaryocytosis is described. The baby was treated by double‐volume exchange transfusion with only a temporary benefit; 2 weeks of steroid treatment were unsuccessful but the platelet count did increase transiently after infusion of random donor platelets.
Nicola Bizzaro, Gianfranco Dianese
openaire   +2 more sources

Neonatal alloimmune thrombocytopenia

Blood Reviews, 1989
Neonatal alloimmune thrombocytopenia (NAIT) occurs when maternal alloantibodies to antigens present on fetal platelets cause their immune destruction resulting in thrombocytopenia in the newborn infant or fetus. Bleeding may be severe; intracranial haemorrhage and permanent neurological damage are the most serious complications. Despite the severity of
M Contreras, P.O Skacel
openaire   +3 more sources

Management of alloimmune thrombocytopenia

Vox Sanguinis, 2007
Fetal alloimmune thrombocytopenia is caused by maternal sensitization to paternally-derived antigens on fetal platelets, most commonly HPA-1a.1 It occurs in approximately 1 in 1000 live births and is the commonest cause of severe fetal and neonatal thrombocytopenia, and of intracranial hemorrhage in neonates born at term.2 Since there is currently no ...
H H H, Kanhai   +34 more
openaire   +2 more sources

Red‐blood‐cell alloimmunization and prophylactic antigen matching for transfusion in patients with warm autoantibodies

Vox Sanguinis, 2020
Warm autoantibodies (WAA) are antibodies that react with an antigen on a patient’s own red‐blood‐cells and can complicate compatibility testing whether or not they cause clinical haemolysis. The goal of this study was to understand the overall prevalence
M. Delaney   +11 more
semanticscholar   +1 more source

Platelet transfusion: Alloimmunization and refractoriness.

Seminars in hematology (Print), 2020
The transfusion of platelets for both prophylaxis and treatment of bleeding is relevant to all areas of medicine and surgery. Historically, guidance regarding platelet transfusion has been limited by a lack of good quality clinical trials and so has been
Catherine Prodger   +4 more
semanticscholar   +1 more source

Practice Bulletin No. 181: Prevention of Rh D Alloimmunization.

Obstetrics and Gynecology, 2017
Advances in the prevention and treatment of Rh D alloimmunization have been one of the great success stories of modern obstetrics. There is wide variation in prevalence rates of Rh D-negative individuals between regions, for example from 5% in India to ...

semanticscholar   +1 more source

Transplantation of the alloimmunized patient

Transplant Immunology, 1994
New information regarding the specificity of T and B cell recognition of antigens, such as allogeneic HLA molecules, has greatly affected the view on matching and evaluation of alloimmunization in clinical transplantation. We shall deal separately with T and B cell recognition of HLA antigens.
openaire   +3 more sources

RETIRED: Prevention of Rh Alloimmunization

Journal of Obstetrics and Gynaecology Canada, 2003
To provide guidelines on use of anti-D prophylaxis to optimize prevention of rhesus (Rh) alloimmunization in Canadian women.Decreased incidence of Rh alloimmunization and minimized practice variation with regards to immunoprophylaxis strategies.The Cochrane Library and MEDLINE were searched for English-language articles from 1968 to 2001, relating to ...
R. D. Wilson   +15 more
openaire   +2 more sources

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