Results 61 to 70 of about 5,537,837 (195)

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Orthodentine‐osteodentine and osteocytic‐anosteocytic transition inferred from Silurian stem chondrichthyan dermal jawbones with ever‐white teeth overgrown by brown denticles

Developmental Dynamics, EarlyView.
Abstract Background The dentigerous jawbones of a 423‐million‐year‐old stem chondrichthyan (ischnacanthid acanthodian) carry a characteristic combination of multi‐row non‐shedding white teeth with brownish overgrowing denticles. The color distinction makes it a good model for observing the interaction between two odontode lineages, but the nature of ...
Jia‐Cih Kang, Henning Blom, Tiiu Märss, Donglei Chen   +3 more
wiley   +1 more source

Modeling climate adaptive habitat connectivity for conservation planning in Colombia

Ecography, EarlyView.
To remain effective under global change, conservation decisions must anticipate shifting climates, species responses to climate change and the dispersal pathways needed to track suitable climate. Yet most assessments of ecological connectivity do not consider how the landscape will change, or, if they do, they only consider a single future time point ...
Lei Song, Amy E. Frazier, Patrick R. Roehrdanz, Wenxin Yang, Joana M. Krieger, Nickolas McManus, Elkin A. Noguera‐ Urbano, Susana Rodriguez‐ Buritica, Dan Willett   +8 more
wiley   +1 more source

Long‐Term Operation of Photovoltaic Power Stations Promotes Soil Carbon Sequestration but Induces Stoichiometric C:N:P Imbalance in Desert Ecosystems

Land Degradation &Development, EarlyView.
ABSTRACT Soil carbon‐nitrogen‐phosphorus (C:N:P) stoichiometry governs nutrient cycling and carbon sequestration in desert ecosystems, yet how large‐scale photovoltaic (PV) deployment, a cornerstone of global carbon neutrality, shifts these stoichiometric balances and whether such shifts enhance or degrade long‐term land function remain unresolved over
Anlin Wang, Fenghua Sun, Longfei Chen, Hong Yang, Panxing He, Zhanjun Wang, Xudong Wu, D. M. Sabra, Rui Ma, Jianhua Xiao   +9 more
wiley   +1 more source

Home and away: allometry and climate drive morphology of European rabbits in their native and introduced range

Oikos, EarlyView.
Climatic conditions shape phenotypic evolution by driving adaptations that optimise organismal function. Invasive species provide valuable systems to study these processes, as they often encounter novel climatic conditions in their introduced ranges. The European rabbit Oryctolagus cuniculus, native to the Iberian Peninsula, has established populations
Rishab Pillai, Natasha Lee Hiotis, Christine Böhmer, Cécile Callou, Thomas J. Nelson, Irina Ruf, Thomas J. Sanger, Julia Schaar, Kévin Le Verger, Madeleine Geiger, Brian Kraatz, Emma Sherratt   +11 more
wiley   +1 more source

Informing the potential of mature temperate forests as natural climate solutions: Changed fine root biomass and morphology under elevated CO2

PLANTS, PEOPLE, PLANET, EarlyView.
The land carbon sink absorbs approximately 25% of anthropogenic CO2 emissions, with forests accounting for most. Managing forests as Natural Climate Solutions is therefore a societal imperative, requiring models of where and how long carbon resides within these ecosystems. We investigated the effects of elevated CO2 on fine roots, the primary source of
Grace Handy, Angeliki Kourmouli, Marie Arnaud, Carolina Mayoral, Richard J. Norby, Michaela K. Reay, Sami Ullah, Iain P. Hartley, R. Liz Hamilton, Robert Grzesik, Andy R. Smith, Elena Vanguelova, A. Rob MacKenzie, Adriane Esquivel‐Muelbert   +13 more
wiley   +1 more source

Peri‐urban agroforestry for climate mitigation in West Africa: Structural diversity and functional traits as key drivers of carbon storage

PLANTS, PEOPLE, PLANET, EarlyView.
Peri‐urban areas in West Africa are expanding rapidly, often with limited planning and growing exposure to climate risks. Our study shows that agroforestry systems in these landscapes, especially diverse home gardens, can store substantial amounts of carbon when they include structurally complex stands and species with traits that favor biomass ...
Sèdoami Flora Dogbo, Kolawolé Valère Salako, Sylvanus Mensah, Gafarou Agoundé, Kangbéni Dimobe, Achille Ephrem Assogbadjo, Jens Gebauer, Constant Yves Adou Yao, Romain Glèlè Kakaï   +8 more
wiley   +1 more source

Climate‐Modulated Particle Toxicity: Acute Exposure to an Environmentally Informed Microplastic Mixture Induces Sex‐Dependent Systemic Reorganization in Swiss Mice

Environmental Toxicology, EarlyView.
ABSTRACT Microplastic (MP) pollution is widely recognized as an emerging environmental threat. Yet, most studies still rely on controlled experimental conditions that poorly reflect environmental complexity, potentially underestimating risks under realistic scenarios, particularly during short‐term exposures. Here, we tested whether acute oral exposure
Guilherme Malafaia, Rafaela Ribeiro de Brito, Aline Sueli de Lima de Rodrigues, Omar Cruz Santiago, Andrés Hugo Arias, Thiarlen Marinho da Luz   +5 more
wiley   +1 more source

Integrating large mammalian herbivores into Dynamic Global Vegetation Models: Status and next steps

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Zoogeochemistry, the study of how animals influence elemental cycling within ecosystems, bridges the fields of zoology, ecology and biogeochemistry. Yet, most terrestrial ecosystem models, especially Dynamic Global Vegetation Models (DGVMs), remain largely plant‐centric
Yue Cheng, Joanne Alice O'Keeffe, Andrew J. Abraham, Jesper Riis Christiansen, Frederik Nygaard Philipsen, Klaus Steenberg Larsen, Fabio Berzaghi, Carsten W. Mueller, Lars Vesterdal, Jeppe A. Kristensen, Elizabeth Le Roux   +10 more
wiley   +1 more source