Results 1 to 10 of about 13,016 (292)
Allometric scaling in-vitro. [PDF]
Sci Rep, 2017 AbstractAbout two decades ago, West and coworkers established a model which predicts that metabolic rate follows a three quarter power relationship with the mass of an organism, based on the premise that tissues are supplied nutrients through a fractal distribution network. Quarter power scaling is widely considered a universal law of biology and it is
Ahluwalia A.
europepmc +8 more sources
Sizing up allometric scaling theory. [PDF]
PLoS Computational Biology, 2008 Metabolic rate, heart rate, lifespan, and many other physiological properties vary with body mass in systematic and interrelated ways. Present empirical data suggest that these scaling relationships take the form of power laws with exponents that are ...
Van M Savage +2 more
doaj +8 more sources
Application of Allometric Scaling to Nanochelator Pharmacokinetics. [PDF]
ACS Omega, 2023 Deferoxamine (DFO) is an effective FDA-approved iron chelator; however, its use is considerably limited by off-target toxicities and an extremely cumbersome dose regimen involving daily infusions. The recent development of a deferoxamine-based nanochelator (DFO-NP) with selective renal excretion has shown promise in ameliorating iron overload and ...
Jones G, Zeng L, Kim J.
europepmc +5 more sources
Allometric Scaling of physiologically-relevant organoids. [PDF]
Sci Rep, 2019 Abstract The functional and structural resemblance of organoids to mammalian organs suggests that they might follow the same allometric scaling rules. However, despite their remarkable likeness to downscaled organs, non-luminal organoids are often reported to possess necrotic cores due to oxygen diffusion limits.
Magliaro C, Rinaldo A, Ahluwalia A.
europepmc +9 more sources
Allometric scaling in scientific fields [PDF]
Scientometrics, 2017 8 pages, 5 ...
Menghui Li, Chensheng Wu, Jinshan Wu
exaly +3 more sources
Pharmacokinetics of Monoclonal Antibodies in Pediatrics: Model-Based Investigation on Allometric Scaling Exponents [PDF]
PharmaceuticsMethods: This study explored key study design factors that could impact the precision of pediatric pharmacokinetics (PK) estimation. A virtual pediatric population was constructed, incorporating diverse body weight distribution sourced from the U.S ...
Elvis K. Danso +3 more
doaj +2 more sources
Allometric scaling relationships in mouse placenta. [PDF]
J R Soc Interface, 2022 Fetal growth and maturation are highly intertwined with placental development during pregnancy. Here we used placental vascular morphology measurements (depth and span) as well as the umbilical artery (UA) diameter of previously published studies on three different mouse strains (C57BL6/J, CD-1 and BALB/c), which were exposed to different conditions ...
Saghian R +8 more
europepmc +3 more sources
Allometric scaling and accidents at work. [PDF]
Int J Occup Saf Ergon, 2016 Allometry is the knowledge concerning relations between the features of some beings, like animals, or cities. For example, the daily energy rate is proportional to a mass of mammals rise of 3/4. This way of thinking has spread quickly from biology to many areas of research concerned with sociotechnical systems.
Cempel C, Tabaszewski M, Ordysiński S.
europepmc +4 more sources
Functional Trait Space and Multiscale Allometric Scaling of Different Architectural Types in Malus [PDF]
PlantsTree architecture is a critical determinant of plant performance, light capture, biomechanical stability, and resource allocation. However, the multidimensional functional trait space and multiscale allometric scaling mechanisms underlying different ...
Yuerong Fan +3 more
doaj +2 more sources
Allometric scaling of biological rhythms in mammals [PDF]
Biological Research, 2005 A wide spectrum of cyclic functions in terrestrial mammals of different size, from the 3-gram shrew to the 3-ton elephant, yields an allometric exponent around 0.25, which is correlated _ as a kind of common denominator _ with the specific metabolic rate.
Bruno Günther, Enrique Morgado
doaj +4 more sources