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Rethinking Human Energy Metabolism [PDF]

Current Issues in Molecular Biology
For a long time, glycolysis and mitochondrial oxidative phosphorylation were opposed to each other. Glycolysis works when there is a lack of oxygen; the mitochondria supply ATP in an oxygen environment.
Alexander Panov, Vladimir Mayorov, Sergey Dikalov, Alexandra Krasilnikova, Lev Yaguzhinsky   +4 more
doaj   +2 more sources

Apelin and energy metabolism [PDF]

Frontiers in Physiology, 2015
A wide range of adipokines identified over the past years has allowed considering white adipose tissue as a secretory organ closely integrated into overall physiological and metabolic control.
Chantal eBertrand, Philippe eValet, Isabelle eLaurell   +2 more
doaj   +3 more sources

Energy Metabolism and Aging

The World Journal of Men's Health, 2021
Aging is strongly related to energy metabolism, but the underlying processes and mechanisms are complex and incompletely understood. Restricting energy intake and reducing metabolic rate can slow the rate of aging and extend longevity, implying a ...
Andrzej Bartke, Savannah Brannan, Erin Hascup, Kevin Hascup, Justin Darcy   +4 more
doaj   +3 more sources

Energy metabolism and spermatogenesis

Heliyon
Infertility has become a significant health burden around the globe as it is believed that 15 % of married couples struggle with infertility, with half of the problem accrued to the male.
Damilare Emmanuel Rotimi, Matthew Iyobhebhe, Elizabeth Temidayo Oluwayemi, Olasunkanmi Peter Olajide, Bolanle Adenike Akinsanola, Ikponmwosa Owen Evbuomwan, Rotdelmwa Maimako Asaleye, Oluwafemi Adeleke Ojo   +7 more
doaj   +3 more sources

Energy Metabolism and Diet [PDF]

Nutrients, 2021
Energy metabolism at whole body and cellular, and even organelle (i [...]
Nieuwenhuizen, Arie G., van Schothorst, Evert M.   +1 more
openaire   +3 more sources

Chemerin: A Functional Adipokine in Reproductive Health and Diseases

Biomedicines, 2022
As a multifaceted adipokine, chemerin has been found to perform functions vital for immunity, adiposity, and metabolism through its three known receptors (chemokine-like receptor 1, CMKLR1; G-protein-coupled receptor 1, GPR1; C-C motif chemokine receptor-
Ming Yu, Yali Yang, Chen Huang, Lei Ge, Li Xue, Zhonglin Xiao, Tianxia Xiao, Huashan Zhao, Peigen Ren, Jian V. Zhang   +9 more
doaj   +1 more source

The Insulin-like Growth Factor System and Colorectal Cancer

Life, 2022
Insulin-like growth factors (IGFs) are peptides which exert mitogenic, endocrine and cytokine activities. Together with their receptors, binding proteins and associated molecules, they participate in numerous pathophysiological processes, including ...
Nikola Gligorijević, Zorana Dobrijević, Miloš Šunderić, Dragana Robajac, Danilo Četić, Ana Penezić, Goran Miljuš, Olgica Nedić   +7 more
doaj   +1 more source

mTOR hypoactivity leads to trophectoderm cell failure by enhancing lysosomal activation and disrupting the cytoskeleton in preimplantation embryo

Cell & Bioscience, 2023
Background Metabolic homeostasis is closely related to early impairment of cell fate determination and embryo development. The protein kinase mechanistic target of rapamycin (mTOR) is a key regulator of cellular metabolism in the body. Inhibition of mTOR
Chiyuan Ma, Qin Li, Yuxin Yang, Lei Ge, Jiaxuan Cai, Juan Wang, Maoxian Zhu, Yue Xiong, Wenya Zhang, Jingtong Xie, Yujing Cao, Huashan Zhao, Qing Wei, Chen Huang, Junchao Shi, Jian V. Zhang, Enkui Duan, Xiaohua Lei   +17 more
doaj   +1 more source

An Antagonistic Peptide of Gpr1 Ameliorates LPS-Induced Depression through the Hypothalamic-Pituitary-Ovarian Axis

Biomolecules, 2021
Depression affects the reproductive axis at the hypothalamus and pituitary levels, which has a significant impact on female fertility. It has been reported that G protein-coupled receptor 1 (Gpr1) mRNA is expressed in both the hypothalamus and ovaries ...
Rongrong Li, Chiyuan Ma, Yue Xiong, Huashan Zhao, Yali Yang, Li Xue, Baobei Wang, Tianxia Xiao, Jie Chen, Xiaohua Lei, Baohua Ma, Jian Zhang   +11 more
doaj   +1 more source

Effects of Regular Brazil Nut (Bertholletia excelsa H.B.K.) Consumption on Health: A Systematic Review of Clinical Trials

Foods, 2022
The Brazil nut (BN) is a promising food due to its numerous health benefits, but it is still necessary to systematically review the scientific evidence on these benefits. Thus, we examined the effects of regular BN consumption on health markers in humans
Alessandra da Silva, Brenda Kelly Souza Silveira, Brenda Vieira Machado de Freitas, Helen Hermana M. Hermsdorff, Josefina Bressan   +4 more
doaj   +1 more source