Results 101 to 110 of about 13,016 (292)

Allometric scaling for predicting human drug clearance [PDF]

open access: yes, 2005
Various modified methods have been proposed in response to criticisms regarding the practical applicability of allometric scaling, which is one of the most widely used approaches in predicting human drug clearance based on data from animal species.
Tang, Huadong
core  

Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs

open access: yesThe Anatomical Record, EarlyView.
Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy   +3 more
wiley   +1 more source

A model for allometric scaling of mammalian metabolism with ambient heat loss

open access: yesIntegrative Medicine Research, 2016
Background: Allometric scaling, which represents the dependence of biological traits or processes on body size, is a long-standing subject in biological science.
Ho Sang Kwak, Hong G. Im, Eun Bo Shim
doaj   +1 more source

Comparative cranial biomechanics reveal macroevolutionary trends in theropod dinosaurs, with emphasis on Tyrannosauroidea

open access: yesThe Anatomical Record, EarlyView.
Abstract Tyrannosaurus is viewed as a model organism in vertebrate paleontology, with numerous studies analyzing its feeding biomechanics. Nonetheless, the evolution of this feeding performance has been under‐addressed in Tyrannosauroidea, especially in basal tyrannosauroids. Here we used muscle‐force reconstruction and finite element analysis (FEA) to
Evan Johnson‐Ransom   +4 more
wiley   +1 more source

Data from: Allometric convergence in savanna trees and implications for plant scaling models in variable ecosystems [PDF]

open access: yes, 2013
Theoretical models of allometric scaling provide frameworks for understanding and predicting how and why the morphology and function of organisms vary with scale.
Bentley, Lisa P.   +3 more
core   +1 more source

Osteohistology of two phorusrhacids reveals uninterrupted growth strategy

open access: yesThe Anatomical Record, EarlyView.
Abstract Phorusrhacidae were apex predators that primarily dominated South America ecosystems for at least 40 million years with their imposing size and predatory lifestyle—yet some aspects of their biology remain poorly understood. Osteohistology is a tool for understanding growth dynamics and biomechanical adaptations.
Lotta Dreyer   +2 more
wiley   +1 more source

allometric scaling

open access: yes
Citation: 'allometric scaling' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15456 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Body Mass Shapes Most Life History Traits and a Fast‐Slow Continuum in Amphibians

open access: yesEcology and Evolution
Amphibians have the least studied life histories among vertebrates, although they have unique and the most diverse life histories within this group. We compiled a new dataset on adult body mass and 16 other life history traits of 2069 amphibian species ...
Benjamin Cejp, Eva Maria Griebeler
doaj   +1 more source

Metabolic scaling: exploring the relation between metabolic rate and body size

open access: yesAdvances in Physiology Education
We present an alternative to the traditional classroom lecture on the topics of metabolic scaling, allometric relationships between metabolic rate (MR) and body size, and reasons for rejecting Rubner’s surface “law,” concepts that students have described
Beth Beason-Abmayr, David R. Caprette
doaj   +1 more source

Preclinical Pharmacokinetics of MI-219, a Novel Human Double Minute 2 (HDM2) Inhibitor and Prediction of Human Pharmacokinetics

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2012
Purpose. The two purposes of this study were evaluating preclinical pharmacokinetics of MI-219 and predicting clearance (CL) and volume of distribution at steady-state (Vdss) of MI-219 in humans. Methods.
Peng Zou   +9 more
doaj   +1 more source

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