Results 201 to 210 of about 13,016 (292)

A population pharmacokinetic model using allometric scaling for baricitinib in patients with juvenile idiopathic arthritis. [PDF]

CPT Pharmacometrics Syst Pharmacol
Decker RL, Steven Ernest C, Radtke DB, Wang R, Araújo J, Keller SY, Zhang X.   +6 more
europepmc   +1 more source

Informing the potential of mature temperate forests as natural climate solutions: Changed fine root biomass and morphology under elevated CO2

PLANTS, PEOPLE, PLANET, EarlyView.
The land carbon sink absorbs approximately 25% of anthropogenic CO2 emissions, with forests accounting for most. Managing forests as Natural Climate Solutions is therefore a societal imperative, requiring models of where and how long carbon resides within these ecosystems. We investigated the effects of elevated CO2 on fine roots, the primary source of
Grace Handy, Angeliki Kourmouli, Marie Arnaud, Carolina Mayoral, Richard J. Norby, Michaela K. Reay, Sami Ullah, Iain P. Hartley, R. Liz Hamilton, Robert Grzesik, Andy R. Smith, Elena Vanguelova, A. Rob MacKenzie, Adriane Esquivel‐Muelbert   +13 more
wiley   +1 more source

Prediction of Clearance of Monoclonal and Polyclonal Antibodies and Non-Antibody Proteins in Children: Application of Allometric Scaling. [PDF]

Antibodies (Basel), 2020
Mahmood I.
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Allometric Scaling of Mutual Information in Complex Networks: A Conceptual Framework and Empirical Approach. [PDF]

Entropy (Basel), 2020
Viegas E, Goto H, Kobayashi Y, Takayasu M, Takayasu H, Jensen HJ.   +5 more
europepmc   +1 more source

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani, Laiyi Chua, Wendy J. Komocsar, Amy Larkin, Jordan Johns, Xin Zhang   +5 more
wiley   +1 more source

Allometric Scaling Reveals Evolutionary Constraint on Odonata Wing Cellularity via Critical Crack Length. [PDF]

Adv Sci (Weinh)
Eshghi S, Rajabi H, Shafaghi S, Nabati F, Nazerian S, Darvizeh A, Gorb SN.   +6 more
europepmc   +1 more source

Allometric scaling patterns among the human coronary artery tree, myocardial mass, and coronary artery flow. [PDF]

Physiol Rep, 2020
Choi JH, Kim E, Kim HY, Lee SH, Kim SM.
europepmc   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Allometric scaling for left ventricular mass and geometry in male and female athletes of mixed and endurance sports. [PDF]

Echo Res Pract
Oxborough D, McDerment D, George KP, Johnson C, Morrison B, Parry-Williams G, Papatheodorou E, Sharma S, Cooper R.   +8 more
europepmc   +1 more source