Results 171 to 180 of about 13,480 (299)

Drivers of metabolic density‐dependence: how resource availability and conspecific cues affect phytoplankton metabolism

open access: yesOikos, EarlyView.
Metabolism is density‐dependent from unicellular to multicellular organisms. Understanding what drives metabolic suppression is important to explain population growth given the link between metabolism and biomass production. In the simplest scenario, metabolic suppression is caused by a reduction in resource availability with increasing population ...
Ricardo Estevens   +2 more
wiley   +1 more source

Cell type specific allometry controls sex-differences in Drosophila organ size. [PDF]

open access: yesGenetics
Pal S   +8 more
europepmc   +1 more source

Plasma Lidocaine Concentrations During Intravenous Lidocaine Infusion Therapy in the Pediatric Population—A Scoping Review

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles   +3 more
wiley   +1 more source

New perspectives on head and neck allometry and ecomorphology in tetrapods. [PDF]

open access: yesBiol Rev Camb Philos Soc
Maher AE   +4 more
europepmc   +1 more source

Informing the potential of mature temperate forests as natural climate solutions: Changed fine root biomass and morphology under elevated CO2

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The land carbon sink absorbs approximately 25% of anthropogenic CO2 emissions, with forests accounting for most. Managing forests as Natural Climate Solutions is therefore a societal imperative, requiring models of where and how long carbon resides within these ecosystems. We investigated the effects of elevated CO2 on fine roots, the primary source of
Grace Handy   +13 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani   +5 more
wiley   +1 more source

Tempo and drivers of 3D eye size evolution in temperate butterflies. [PDF]

open access: yesEvol Lett
Halali S   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy