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The G Protein Inhibitor YM-254890 is an Allosteric Glue. [PDF]

open access: yesJ Mol Biol
Trent T   +3 more
europepmc   +1 more source
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Thrombin allostery

Physical Chemistry Chemical Physics, 2007
Thrombin is a Na(+)-activated, allosteric serine protease that plays multiple functional roles in blood pathophysiology. Binding of Na(+) is the major driving force behind the procoagulant, prothrombotic and signaling functions of the enzyme. This review summarizes our current understanding of the molecular basis of thrombin allostery with special ...
Enrico, Di Cera   +4 more
openaire   +2 more sources

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