Results 51 to 60 of about 53,713 (267)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Role of Seed Layer in Growing Atomically Flat TiTe2/Sb2Te3 Heterostructure Thin Films at the Wafer Scale

Advanced Materials Interfaces
Chalcogenide phase‐change materials (PCMs) are a leading candidate for advanced memory and computing applications. Epitaxial‐like growth of chalcogenide thin films at the wafer scale is important to guarantee the homogeneity of the thin film but is ...
Chao Nie, Xueyang Shen, Junying Zhang, Chenyu Wen, Yuxin Du, Yazhi Xu, En Ma, Xiaozhe Wang, Riccardo Mazzarello, Wei Zhang, Jiang‐Jing Wang   +10 more
doaj   +1 more source

Imaging individual solute atoms at crystalline imperfections in metals

New Journal of Physics, 2019
Directly imaging all atoms constituting a material and, maybe more importantly, crystalline defects that dictate materials’ properties, remains a formidable challenge.
Shyam Katnagallu, Leigh T Stephenson, Isabelle Mouton, Christoph Freysoldt, Aparna P A Subramanyam, Jan Jenke, Alvin N Ladines, Steffen Neumeier, Thomas Hammerschmidt, Ralf Drautz, Jörg Neugebauer, François Vurpillot, Dierk Raabe, Baptiste Gault   +13 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Atomistic Understanding of 2D Monatomic Phase‐Change Material for Non‐Volatile Optical Applications

Advanced Science
Elemental antimony (Sb) is a promising material for phase‐change memory, neuromorphic computing, and nanophotonic applications, because its compositional simplicity prevents phase segregation upon extensive programming. Scaling down the film thickness is
Hanyi Zhang, Xueqi Xing, Jiang‐Jing Wang, Chao Nie, Yuxin Du, Junying Zhang, Xueyang Shen, Wen Zhou, Matthias Wuttig, Riccardo Mazzarello, Wei Zhang   +10 more
doaj   +1 more source

New TiTaNbZrMo high-entropy alloys for metallic biomaterials

Materials Research Express, 2021
The advantages of high entropy alloy with good comprehensive properties provide a potential opportunity to explore and develop new alloys suitable for human implantation.
Chenwei Li, Ying Ma, Xu Yang, Minghao Hou   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Alloy and Process Design of Metallic Materials

Metals, 2023
Metallic materials have witnessed substantial developments over the past two decades [...]
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source