Results 231 to 240 of about 62,031 (280)

A2A Adenosine Receptor Agonists With Last‐Step Enzymatic 18F‐Labelling Potential (Fluorinase) for Positron Emission Tomography (PET)

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 5, 7 February 2026.
This study exploits the comparable binding tolerances between the fluorinase enzyme and the A2A adenosine receptor towards the development of novel C‐2 functionalised 5′‐fluorodeoxy‐adenosine (FDA)‐based agonists with enzymatic 18F‐labelling capability for positron emission tomography (PET).
Nicolas Charalambous   +6 more
wiley   +1 more source

Organoselenium-based Schiff bases and amidic acid derivatives as promising anticancer agents targeting breast cancer by downregulating BCL-2: design, synthesis, and biological evaluation. [PDF]

open access: yesRSC Adv
Shaaban S   +11 more
europepmc   +1 more source

Stereospecific Transition‐Metal‐Free Alkylation of Chiral Non‐Racemic Secondary Tosylates with Cyanohydrins: Convenient Access to Enantiomerically Enriched α‐Tertiary Ketones

open access: yesAngewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A stereospecific, transition‐metal‐free SN2 alkylation of cyanohydrins with chiral non‐racemic secondary tosylates is reported, providing efficient access to enantioenriched α‐tertiary ketones. The method exhibits broad substrate scope, operational simplicity, and excellent stereospecificity, including stereoconvergent reactions of E/Z mixtures of ...
Jinjin Ma   +3 more
wiley   +1 more source

Light-driven radical copper-catalyzed allylic amination via allylic copper intermediates. [PDF]

open access: yesNat Commun
Luo H   +9 more
europepmc   +1 more source

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