Results 41 to 50 of about 40,199 (217)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Pair of Associated η-Ricci–Bourguignon Almost Solitons with Generalized Conformal Killing Potential on Sasaki-like Almost Contact Complex Riemannian Manifolds

Mathematics
The subject of this study is almost contact complex Riemannian manifolds, also known as almost contact B-metric manifolds. The considerations are restricted to a special class of these manifolds, namely those of the Sasaki-like type, because of their ...
Mancho Manev
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Totally Umbilical Radical Screen Transversal Half Lightlike Submanifolds of Almost Contact B-metric Manifolds [PDF]

, 2021
The present paper is a continuation of our previous work, where a class of half lightlike submanifolds of almost contact B-metric manifolds was introduced. We study curvature properties of totally and screen totally umbilical such submanifolds as well as of the corresponding semi-Riemannian submanifolds with respect to the associated B-metric.
openaire   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Pair of Associated η-Ricci–Bourguignon Almost Solitons with Vertical Torse-Forming Potential on Almost Contact Complex Riemannian Manifolds

Mathematics
Each of the studied manifolds has a pair of B-metrics, interrelated by an almost contact structure. The case where each of these metrics gives rise to an η-Ricci–Bourguignon almost soliton, where η is the contact form, is studied.
Mancho Manev
doaj   +1 more source

Evaluation of the Potential of Laser Shock Peening Compared with Cold Expansion for Improving Fatigue Resistance of Riveted Lap Joints of Aerospace Grade 7175 Al Alloy

Advanced Engineering Materials, EarlyView.
This study investigates laser shock peening for enhancing fatigue performance of riveted aerospace aluminum joints. A comparative approach with cold expansion combines fatigue testing and synchrotron X‐ray methods. Integrating mechanical testing with residual stress and strain characterization provides insights into how different treatments affect the ...
Ogün Baris Tapar, David Osman Busse, Maximilian Sprengel, Domenico Furfari, Marc‐André Nielsen, Guilherme Abreu Faria, Jérémy Epp   +6 more
wiley   +1 more source

Totally Contact Umbilical Radical Transversal Lightlike Submanifolds Of An Almost Contact Manifold With B-Metric

JOURNAL OF ADVANCES IN MATHEMATICS, 2017
In the present paper, we study the geometry of totally contact umbilical radical transversal lightlike submanifolds and totally contact umbilical CR- submanifold of an indenite Sasaki-like almost contact manifold with B-metric. We nd the necessary and sucient condition for the characterization of the induced connection to be a metric connection ...
Anu Devgan, R. K. Nagaich
openaire   +2 more sources

Hybrid Auxetic Architectures: Integrating Curvature‐Driven Design for Enhanced Mechanical Tunability and Structural Performance

Advanced Engineering Materials, EarlyView.
Curvature‐tuned auxetic lattices are designed, fabricated, and mechanically characterized to reveal how geometric curvature governs stretchability, stress redistribution, and Poisson's ratio evolution. Photoelastic experiments visualize stress pathways, while hyperelastic simulations quantify deformation mechanics.
Shuvodeep De, Giovanni Meli, Meysam Khalighian, Anahita Emami   +3 more
wiley   +1 more source

A quarter-symmetric metric connection on almost contact B-metric manifolds

Filomat, 2019
The aim of this paper is to study the notion of a quarter-symmetric metric connection on an almost contact B-metric manifold (M,?,?,?,g). We obtain the relation between the Levi-Civita connection and the quarter-symmetric metric connection on (M,?,?,?,g).We investigate the curvature tensor, Ricci tensor and scalar curvature tensor with ...
openaire   +2 more sources