Results 101 to 110 of about 6,768,037 (271)

Almost periodic random sequences in probability

open access: yes, 2017
This paper is concerned with almost periodic random sequences in probability. Some basic and fundamental properties of such sequences are established.
Paul H. Bezandry
core   +2 more sources

Partial sequencing of the bottle gourd genome reveals markers useful for phylogenetic analysis and breeding

open access: yesBMC Genomics, 2011
Background Bottle gourd [Lagenaria siceraria (Mol.) Standl.] is an important cucurbit crop worldwide. Archaeological research indicates that bottle gourd was domesticated more than 10,000 years ago, making it one of the earliest plants cultivated by man.
Wang Sha   +8 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Almost overcomplete and almost overtotal sequences in Banach spaces

open access: yes, 2014
We introduce the new concepts of almost overcomplete sequence in a Banach space and almost overtotal sequence in a dual space. We prove that any of such sequences is relatively norm-compact and we present several applications of this ...
C. Zanco, V. P. Fonf
core   +1 more source

Robust secure image encryption scheme using a 6D hyper-chaotic system with dynamic parameters and DNA encoding

open access: yesFranklin Open
In this paper, we suggest a highly efficient and safe image encryption algorithm that is synergistic in combining a new 6D hyper-chaotic system with dynamically encoded DNA. Our method has two innovations to overcome the shortcomings of the current chaos-
Mohammed S. Mahdi   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Almost p-ary sequences

open access: yes, 2020
In this paper we study almost p-ary sequences and their autocorrelation coefficients. We first study the number l of distinct out-of-phase autocorrelation coefficients for an almost p-ary sequence of period n + s with s consecutive zero-symbols. We prove
Yayla, Oğuz, Ozden, Busra
core   +1 more source

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