Results 101 to 110 of about 7,068,142 (272)

On almost asymptotically lacunary statistical equivalence of sequences of sets [PDF]

, 2014
In this paper we study the concepts of Wijsman almost asymptotically statistical equivalent, Wijsman almost asymptotically lacunary statistical equivalent and Wijsman strongly almost asymptotically lacunary equivalent sequences of sets and investigate ...
Ulusu, Uğur
core   +1 more source

Partial sequencing of the bottle gourd genome reveals markers useful for phylogenetic analysis and breeding

BMC Genomics, 2011
Background Bottle gourd [Lagenaria siceraria (Mol.) Standl.] is an important cucurbit crop worldwide. Archaeological research indicates that bottle gourd was domesticated more than 10,000 years ago, making it one of the earliest plants cultivated by man.
Wang Sha, Ehlers Jeffrey D, Liu Yonghua, Wang Baogen, Luo Jie, Wu Xiaohua, Xu Pei, Lu Zhongfu, Li Guojing   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Robust secure image encryption scheme using a 6D hyper-chaotic system with dynamic parameters and DNA encoding

Franklin Open
In this paper, we suggest a highly efficient and safe image encryption algorithm that is synergistic in combining a new 6D hyper-chaotic system with dynamically encoded DNA. Our method has two innovations to overcome the shortcomings of the current chaos-
Mohammed S. Mahdi, Hayder Najm, Amjed Abbas Ahmed, Sumaia Mohammed Al-Ghuribi   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

A duality result for almost split sequences [PDF]

, 1999
Over an artinian hereditary ring R, we discuss how the existence of almost split sequences starting at the indecomposable non-injective preprojective right R-modules is related to the existence of almost split sequences ending at the indecomposable non ...
ANGELERI, LIDIA, H. VALENTA, Valenta, Helmut, Hügel, Lidia   +3 more
core  

Almost p-ary sequences

, 2020
In this paper we study almost p-ary sequences and their autocorrelation coefficients. We first study the number l of distinct out-of-phase autocorrelation coefficients for an almost p-ary sequence of period n + s with s consecutive zero-symbols. We prove
Yayla, Oğuz, Ozden, Busra
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source