Results 181 to 190 of about 1,830,879 (269)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Increasing MRI capacity at a clinical diagnostic centre and a trauma hospital using artificial intelligence-based image reconstruction (AI-IR): a quality improvement project using the Model for Improvement framework. [PDF]

open access: yesBMJ Open Qual
Martin J   +18 more
europepmc   +1 more source

A summability factor theorem by using an almost increasing sequence

open access: yes, 2009
When given an infinite series Pan with the partial sums (sn) and a normal matrix A = (anv), i. e. a lower triangular matrix of non-zero diagonal entries, A defines the sequence-to-sequence transformation, mapping the sequence s = (sn) to As = (An(s)), In this case, by | A |k summability of this infinite series we mean the convergence of the series Pn k?
openaire   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

A programmable ribozyme for RNA signal transduction. [PDF]

open access: yesNat Commun
Lim MYT   +13 more
europepmc   +1 more source

On almost sure behavior of stable subordinators over rapidly increasing sequences

open access: yesТеория вероятностей и ее применения, 2005
Rasbagh Vasudeva   +5 more
openaire   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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