Results 71 to 80 of about 908,104 (274)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Reducibility for a Class of Almost-Periodic Differential Equations with Degenerate Equilibrium Point under Small Almost-Periodic Perturbations

Abstract and Applied Analysis, 2013
This paper focuses on almost-periodic time-dependent perturbations of an almost-periodic differential equation near the degenerate equilibrium point.
Wenhua Qiu, Jianguo Si
doaj   +1 more source

c-Almost periodic type functions and applications

Nonautonomous Dynamical Systems, 2020
In this paper, we introduce several various classes of c-almost periodic type functions and their Stepanov generalizations, where c ∈ ℂ and |c| = 1. We also consider the corresponding classes of c-almost periodic type functions depending on two variables
Khalladi M. T., Kostić M., Pinto M., Rahmani A., Velinov D.   +4 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Asymptotically almost periodic and almost periodic solutions for a class of partial integrodifferential equations

Electronic Journal of Differential Equations, 2006
In this note, we establish the existence of asymptotically almost periodic and almost periodic solutions for a class of partial integrodifferential equations.
Eduardo Hernandez M., Jose Paulo C. dos Santos   +1 more
doaj  

Almost periodic distributions and crystalline measures

Математичні Студії
We study temperate distributions and measures with discrete support in Euclidean space and their Fourier transforms with special attention to almost periodic distributions.
S. Yu. Favorov
doaj   +1 more source

Dynamics of μ -piecewise pseudo almost periodic solutions of neutral-type inertial neural networks models: existence and attractiveness. [PDF]

Cogn Neurodyn, 2022
Ezzinbi K, Mbounja Béssémè F.
europepmc   +1 more source

Almost periodic solution in distribution for stochastic differential equations with Stepanov almost periodic coefficients

, 2017
This paper deals with the existence and uniqueness of ($\mu$-pseudo) almost periodic mild solution to some evolution equations with Stepanov ($\mu$-pseudo) almost periodic coefficients, in both determinist and stochastic cases.
Bedouhene, Fazia, Challali, Nouredine, de Fitte, Paul Raynaud, Mellah, Omar, Smaali, Mannal   +4 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source