Results 101 to 110 of about 451,129 (278)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Pseudo almost periodic solutions for a Lasota-Wazewska model

open access: yesElectronic Journal of Differential Equations, 2016
In this work, we consider a new model describing the survival of red blood cells in animals. Specifically, we study a class of Lasota-Wazewska equation with pseudo almost periodic varying environment and mixed delays.
Samira Rihani   +2 more
doaj  

Attractors and global averaging of non-autonomous reaction-diffusion equations in R^n

open access: yes, 2002
We consider a family of non-autonomous reaction-diffusion equations with almost periodic, rapidly oscillating principal part and nonlinear interactions.
Antoci, F., Prizzi, M.
core   +3 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Almost Periodic Solutions for Impulsive Fractional Stochastic Evolution Equations

open access: yesInternational Journal of Analysis and Applications, 2014
In this paper, we consider the existence of square-mean piecewise almost periodic solutions for impulsive fractional stochastic evolution equations involving Caputo fractional derivative.
Toufik Guendouzi, Lamia Bousmaha
doaj   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Existence and Stability Properties of Almost Periodic Solutions in Discrete Almost Periodic Systems

open access: yesAdvances in Pure Mathematics, 2018
In order to obtain the existence of almost periodic solutions of both linear and nonlinear almost periodic discrete systems: \( x(n+1) = A(n)x(n) \) and \( x_{i}(n+1)=\sum _{j=1}^{m}a_{ij}(n)g_{j}(x_{j}(n)) \quad \text{ for } \quad 1 \le i \le m \), respectively, we shall consider between certain stability properties, which are referred to as uniformly
openaire   +2 more sources

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