Results 51 to 60 of about 1,531,740 (243)
Morphisms and almost-periodicity
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Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
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Strong Stability and Asymptotical Almost Periodicity of Volterra Equations in Banach Spaces
We study strong stability and asymptotical almost periodicity of solutions to abstract Volterra equations in Banach spaces. Relevant criteria are established, and examples are given to illustrate our results.
Xiao Ti-Jun, Chen Jian-Hua
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Almost-periodic solution for BAM neural networks [PDF]
In this paper, we study the existence and uniqueness solution and investigate the conditions that make it almost-periodic solution for BAM neural networks with retarded delays.
Hamid A. Jalab, Rabha W. Ibrahim
doaj
0. Summary. Second-order stationary random sequences, especially if Gaussian, may be of statistical interest because their covariances may, under certain conditions, be consistently estimated with finite realizations of the sequences. It is shown that there is a class of non-stationary random sequences, namely sequences of orthogonal random variables ...
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
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Almost periodic distributions and crystalline measures
We study temperate distributions and measures with discrete support in Euclidean space and their Fourier transforms with special attention to almost periodic distributions.
S. Yu. Favorov
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In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
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Modeling Periodicity or Almost Periodicity in an Inhomogeneous Gamma Point Process [PDF]
We propose a model for the analysis of an inhomogeneous Gamma processes (IGP) with a periodic or almost periodic baseline intensity function and shape parameter greater than zero. The IGP is a generalization of both the nonhomogeneous Poisson process and
Gaitan, Rodrigo Saul
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