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A high proportion of young men in this country suffer from premature baldness. Alopecia is not a disease entity but one of the outstanding features of chronic fluorine poisoning (fluorosis). It is frequently associated with dystrophies of other organs of ectodermal origin, namely, those of the skin and its other appendages, the teeth and nails.
openaire +3 more sources
Pemetrexed is a cornerstone in chemo(immunotherapy) of non‐small cell lung cancer and mesothelioma; however, it is contraindicated in patients with renal impairment due to severe toxicity concerns. Therefore, a large proportion of patients is withheld from effective chemo(immunotherapy).
Nikki de Rouw+18 more
wiley +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia+4 more
wiley +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Establishing the financial burden of alopecia areata and its predictors
Background Alopecia areata (AA) can have a significant impact on wellbeing. Consequently, individuals with AA often seek treatments or products to promote hair regrowth or camouflage their hair loss that incur a financial cost to the individual ...
Fabio Zucchelli+3 more
doaj +1 more source
Alopecia Areata: Review of Epidemiology, Clinical Features, Pathogenesis, and New Treatment Options
Alopecia areata (AA) is a complex autoimmune condition that causes nonscarring hair loss. It typically presents with sharply demarcated round patches of hair loss and may present at any age. In this article, we review the epidemiology, clinical features,
E. Darwin+5 more
semanticscholar +1 more source
Beyond pink ribbons: The unmet needs of women with breast cancer
Abstract Breast cancer is the most frequently diagnosed cancer worldwide. The treatment options for breast cancer can cause side effects and adversely impact quality of life. Side effects, including fatigue, pain, cognitive changes, and psychosocial complications, can be life altering and continue beyond treatment into survivorship.
Laura Feighan+3 more
wiley +1 more source
Role of Topical Ketoconazole in Therapeutic Hair Care Beyond Seborrhoeic Dermatitis and Dandruff
ABSTRACT Ketoconazole shampoo has well‐documented consistent efficacy and safety in treating dandruff and seborrhoeic dermatitis (SD) when compared to other active antidandruff ingredients such as selenium sulphide, corticosteroids and zinc pyrithione.
Aditya K. Gupta+2 more
wiley +1 more source
Variant PADI3 in Central Centrifugal Cicatricial Alopecia
BACKGROUND Central centrifugal cicatricial alopecia (CCCA) is the most common form of scarring alopecia among women of African ancestry. The disease is occasionally observed to affect women in families in a manner that suggests an autosomal dominant ...
L. Malki+20 more
semanticscholar +1 more source
ABSTRACT Background Patients with dermatological immune mediated inflammatory diseases (IMIDs) are increasingly treated with immunosuppressive and ‐modulating drugs. Some of these drugs increase the risk of acquiring infections and more complications can arise during an infection while treated with these agents.
Femke Lieten+8 more
wiley +1 more source