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Alopecia areata [PDF]

Nature Reviews Disease Primers, 2017
Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type.
Pratt, C Herbert, King, Lloyd E, Messenger, Andrew G, Christiano, Angela M, Sundberg, John P   +4 more
openaire   +5 more sources

Dermoscopic Assessment of Nail Alterations in Egyptian Patients with Alopecia Areata [PDF]

Dermatology Practical & Conceptual
Introduction: Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss. Hair and nails have many commonalities related to their development and structure and both can be involved in a range of disorders.
Sara Galal, Radwa Tiranly, Doaa Pessar, Hala Elsadek   +3 more
doaj   +2 more sources

Role of Aire and Notch4 allelic mutations in alopecia areata in C3H/HeJ mice [PDF]

JID Innovations
Human genetic association studies suggest that AIRE (autoimmune regulator gene) and NOTCH4 are directly associated with severe forms of alopecia areata, possibly distinct subtypes of the disease. To determine whether sequence variations in Aire or Notch4
Christopher S. Potter, John P. Sundberg, Kathleen Silva   +2 more
doaj   +2 more sources

Alopecia areata. Diagnostic and therapeutic recommendations of the Polish Society of Dermatology. Part 2: Treatment

Przegląd Dermatologiczny, 2023
The treatment goal in alopecia areata is induction of hair regrowth and halting the progression of the disease. Treatment decisions depend on the severity of the alopecia areata as assessed by the Severity of Alopecia Tool (SALT) or the Alopecia Areata ...
Adriana Rakowska, Lidia Rudnicka, Małgorzata Olszewska, Beata Bergler-Czop, Joanna Czuwara, Ligia Brzezińska-Wcisło, Joanna Narbutt, Waldemar Placek, Barbara Zegarska   +8 more
doaj   +1 more source

Alopecia areata. Diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 1. Diagnosis and severity assessment

Przegląd Dermatologiczny, 2023
The existence of two types of alopecia areata is suggested (probably genetically different): early-onset, with more severe symptoms, longer disease duration, higher tendency to relapse, often with a positive family history, and late-onset, in which the ...
Adriana Rakowska, Lidia Rudnicka, Małgorzata Olszewska, Beata Bergler-Czop, Joanna Czuwara, Ligia Brzezińska-Wcisło, Joanna Narbutt, Waldemar Placek, Barbara Zegarska   +8 more
doaj   +1 more source

Progress in immune pathogenesis and targeted therapy of alopecia areata

Pifu-xingbing zhenliaoxue zazhi, 2023
Alopecia areata is a common clinical non-cicatricial alopecia. Alopecia totalis and generalized alopecia may occur in severe cases. The pathogenesis of alopecia areata is complex, and the treatment is faced with many difficulties.
Jiali WANG, Dantong CHENG, Nana LUO, Pingsheng HAO   +3 more
doaj   +1 more source

Treatment preferences by disease severity in alopecia areata: A cross-sectional survey study [PDF]

JAAD International
Ursula Biba, BS, Katherine Sanchez, BS, Samantha Gregoire, BS, Natasha A. Mesinkovska, MD, PhD, Monique Waldman, PhD, Lisa Anderson, PhD, Arash Mostaghimi, MD, MPA, MPH   +6 more
doaj   +2 more sources

Alopecia Areata as a Proximal Risk Factor for the Development of Comorbid Depression: A Population-based Study

Acta Dermato-Venereologica, 2022
Alopecia areata and depression tend to co-occur; however, their temporal association has not been comprehensively investigated. The aim of this study was to examine the temporal association between alopecia areata and depression.
Dana Tzur Bitan, Daniella Berzin, Khalaf Kridin, Yaron Sela, Arnon Cohen   +4 more
doaj   +1 more source

Serum Zinc Concentration in Patients with Alopecia Areata

Acta Dermato-Venereologica, 2023
Alopecia areata is an autoimmune non-scarring disease in which the exact mechanism that induces loss of immune privilege is unknown. Zinc is important for DNA stability and repair mechanisms that are essential in maintaining normal hair growth.
Jovan Lalosevic, Mirjana Gajic-Veljic, Jelena Lalosevic Misovic, Milos Nikolic   +3 more
doaj   +1 more source

Alopecia Areata Occurring after COVID-19 Vaccination: A Single-Center, Cross-Sectional Study

Vaccines, 2022
Limited data concerning the development of autoimmune skin diseases after COVID-19 vaccination are currently available. Recently, a few reports described the development, worsening or recurrence of alopecia areata after the administration of COVID-19 ...
Francesco Tassone, Simone Cappilli, Flaminia Antonelli, Ruggiero Zingarelli, Andrea Chiricozzi, Ketty Peris   +5 more
doaj   +1 more source