Results 41 to 50 of about 33,525 (245)

Alopecia areata in Eringer cows

, 2010
Alopecia areata is a hair loss disorder in humans, dogs and horses with a suspected autoimmune aetiology targeting anagen hair follicles. Alopecia areata is only sporadically reported in cows.
Rieder, S., Valérie F. Bornand, Timm, Katrin, Flury, C., Claudia Von Tscharner, Gaby Hirsbrunner, Petra J. Roosje, Bornand, Valérie F., Doherr, Marcus, Stefan Rieder, Roosje, Petra, Christine Flury, von Tscharner, C., Anna Oevermann, Cord Drögemüller, Rüfenacht, Silvia, Katrin Timm, Oevermann, Anna, Hirsbrunner, Gabriela, Drögemüller, Cord, Marcus G. Doherr, Silvia Rüfenacht   +21 more
core   +1 more source

Alopecia Areata is Associated with Increased Expression of Heart Disease Biomarker Cardiac Troponin I

Acta Dermato-Venereologica, 2018
The development of androgenetic alopecia is associated with a risk of developing cardiovascular diseases, but the association of alopecia areata with cardiovascular diseases in humans is largely unexplored.
Eddy Hsi Wang, Leopoldo Santos, Xi Yuan Li, Annie Tran, Sandra S.Y. Kim, Katrina Woo, Jerry Shapiro, Kevin J. McElwee   +7 more
doaj   +1 more source

Successful treatment of concomitant alopecia universalis and Crohn’s disease with upadacitinib: A case report

SAGE Open Medical Case Reports, 2023
Alopecia areata is a non-scarring, autoimmune hair loss disorder that is associated with inflammatory bowel disease. Alopecia areata and inflammatory bowel disease may have a common pathogenic mechanism that involves the Janus kinase/STAT pathway.
Leah A Johnston, Cathy Lu, Susan M Poelman   +2 more
doaj   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Electrocardiogram Findings in Patients with Alopecia Areata [PDF]

, 2021
IntroductionWhile autoimmune comorbidities are common in alopecia areata, little is known about comorbid cardiovascular disease. The purpose of this study was to evaluate the incidence of bradyarrhythmia in patients with alopecia areata ...
Lampert, Rachel, Wambier, Carlos, Mesinkovska, Natasha A, Peterson, Danielle, Ahmad, Tariq, Yale, Katerina L, Dai, Feng, King, Brett   +7 more
core   +1 more source

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

Direct Immunofluorescence Studies in Alopecia Areata and Male Pattern Alopecia [PDF]

, 1979
Direct immunofluorescence studies were performed on hairy and alopecic areas of scalp in patients with alopecia areata, alopecia totalis and male pattern alopecia.
Stengel, Fernando, Bystryn, Jean-Claude, Orentreich, Norman   +2 more
core   +1 more source

Alopecia Areata in a Patient Receiving Cemiplimab for Metastatic Cutaneous Squamous Cell Carcinoma

JEADV Clinical Practice, EarlyView.
ABSTRACT Alopecia areata (AA) is an autoimmune disease characterized by non‐scarring hair loss of the scalp and/or body, with an unpredictable and variable clinical course. Its etiology is not entirely understood, although evidence suggests that environmental, immunological, and genetic factors contribute to disease development.
Marco Rubatto, Eleonora Bongiovanni, Veronica Arese, Michela Camilla Milanesio, Alessia Reali, Massimo Chiarpenello, Gianmauro Numico, Marcella Occelli   +7 more
wiley   +1 more source

Trichoscopic Features of Syphilitic Alopecia and Alopecia Areata: A Comparative Study

, 2023
Kasama Tejapira, Nawara Sakpuwadol, Cherrin Pomsoong, Yanisa Ratanapokasatit, Poonkiat Suchonwanit Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Poonkiat ...
Suchonwanit P, Pomsoong C, Tejapira K, Sakpuwadol N, Ratanapokasatit Y   +4 more
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