Results 71 to 80 of about 18,847 (260)

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

open access: yesImmunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

CLINICAL AND MORPHOLOGICAL CHARACTERISTICS OF DISTURBANCES OF LOCAL IMMUNE RESPONSE IN ALOPECIA AREATA ACCORDING TO THE DISEASE ACTIVITY

open access: yesСеченовский вестник, 2010
Aim. Description of morphological characteristics of alopecia areata according to the disease activity.Methods. Skin biopsies from scalp of patients with alopecia areata were studied: expression of CD4+, CD8+, CD68+, interleukin-2 (IL-2), interferon-y ...
G. P. Tereshchenko
doaj  

Serum prolactin levels in dermatological diseases: A case–control study

open access: yesJournal of Dermatology and Dermatologic Surgery, 2015
Background: Recent lines of evidence suggest that prolactin (PRL) as a neurohormone may play a role in the activity of psoriasis and some other immune-mediated diseases.
Nadia Abdalhafid Elsherif   +2 more
doaj   +1 more source

Clinical heterogeneity in vitiligo: Identification of clinical markers based patient clusters

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Vitiligo is a chronic autoimmune disease with heterogeneous clinical presentations. This study analysed 399 patients using hierarchical clustering and identified five phenotypes based on clinical characteristics and lesion distribution. Two groups exhibited high disease activity and extensive involvement.
Laura Galissi   +8 more
wiley   +1 more source

The Relationship between Ocular Alterations and Alopecia Areata [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2015
Background & Aims: Alopecia areata is a chronic inflammatory disorder that affects the hair follicles. The condition most commonly presents with the sudden appearance of non-scarring discrete patches of alopecia on the scalp.
Ramin Taheri   +4 more
doaj  

Nikolsky’s sign - a rare form of alopecia areata

open access: yesVestnik Dermatologii i Venerologii, 2017
Two case reports of rare form of alopecia areata - Nikolsky’s sign - were presented. This disease is often associated with nerve system pathology (schizophrenia, epilepsy, hysteroid reactions). A special feature of first monitoring was the combination of
A. N. Mareeva, I. N. Kondrakhina
doaj   +1 more source

The neglected majority: Inverse relationship between prevalence and global research activity of 15 dermatological diseases

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Oliver Brandt   +3 more
wiley   +1 more source

Addiction and chronic skin diseases: A Pan‐European study on prevalence, associations and patient impact

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This pan‐European study reveals high rates of addiction in patients with chronic skin diseases. Smoking, alcohol, drug use, gambling, and internet addiction were prevalent and associated with quality of life, demographics, and region. The findings support integrating addiction screening into dermatologic care to improve outcomes.
Stefanie Ziehfreund   +73 more
wiley   +1 more source

A Case of Alopecia Areata Treated with Bee Venom and Carthami Flos Herbal Acupuncture

open access: yesJournal of Pharmacopuncture, 2004
Objective : Alopecia areata is a common disease and the difficulty of its medical management is well known. This study was designed to investigate the effect of bee venom and Carthami Flos herbal acupuncture.
Kim Kyung-Woon   +5 more
doaj   +1 more source

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