Results 81 to 90 of about 23,251 (236)

Dupilumab's Real‐World Efficacy and Safety Across Age Groups for Children and Adolescents With Paediatric Atopic Dermatitis

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives Dupilumab is an anti‐interleukin (IL)‐4 receptor (IL‐4Rα) monoclonal antibody used to manage atopic dermatitis (AD). There is a paucity of real‐world Australian data for dupilumab in paediatric AD, especially regarding differences in clinical profiles between age groups.
Paul Sun Woo Kim, Jacqueline Tu, Kelvin Truong, Gloria Fong, William Luu, Peter Barclay, Melanie Wong, Li‐Chuen Wong   +7 more
wiley   +1 more source

Assessment of Interleukin-17A and Interleukin-2 Serum Levels in Patients with Alopecia Areata

مجلة الكوفة الطبية
Background: Alopecia areata (AA) is a condition that leads to the loss of hair in the part of the body due to the destruction of hair follicles, and causing patchy, non-scarring hair loss.
Sajjad M. Alfadul, Israa Abdul Wahad Dheeb, Ghada Basal Ali   +2 more
doaj   +1 more source

Impact of Dermatology Consult on Inpatient and Acute Care Management of Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
Natalie Baker, Baraa Hijaz, Allison Holt, Joseph Ebriani, Bethany J. Brumbaugh, Michael Stephens, John Trinidad, Arash Mostaghimi, Daniela Kroshinsky, Steven T. Chen   +9 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

The causal relationship between gut microbiota and alopecia areata: a Mendelian randomization analysis

Frontiers in Microbiology
BackgroundIncreasing evidence suggests a robust correlation between the gut microbiome and alopecia areata. In light of the extensive diversity of gut microbiota, this study aims to utilize state-of-the-art and comprehensive data to explore the causative
Dezhao Bi, Dezhao Bi, Jin Tong Tey, Jin Tong Tey, Dan Yao, Dan Yao, Yutian Cao, Yutian Cao, Minyu Qian, Minyu Qian, Jianxin Shi, Shun Guo, Shun Guo   +12 more
doaj   +1 more source

A case of new-onset vitiligo in a patient on tofacitinib and brief review of paradoxical presentations with other novel targeted therapies [PDF]

, 2020
With recent advancements in the understanding of vitiligo pathogenesis, Janus kinase (JAK) inhibitors have emerged as a promising new treatment modality, but their effects remain incompletely elucidated.
Alikhan, Mujahed, Jogi, Reena, Nguyen, Julie K, Patel, Anisha B, Schlichte, Megan J   +4 more
core  

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

Allergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez, Jesús Gay‐Mimbrera, Viviana Dávila‐Flores, Helen He, Jerry Zhou, Irene Rivera‐Ruiz, Pedro J. Gómez‐Arias, Juan de Luque‐Fernández, Benjamin Ungar, Emma Guttman‐Yassky, Juan Ruano   +10 more
wiley   +1 more source

Patterns of insurance coverage for wigs in patients with alopecia areata: a cross-sectional survey

International Journal of Women's Dermatology, 2023
Ogechi Ezemma, BA, Shivali Devjani, MS, Aidan Lee, Kristen J. Kelley, BA, Lisa Anderson, PhD, Nicole Friedland, BA, Maryanne Senna, MD   +6 more
doaj   +1 more source

Fármacos y productos naturales útiles en el tratamiento de la alopecia y el cabello dañado [PDF]

, 2018
Este trabajo consiste en una revisión actual sobre la alopecia y sus posibles tratamientos. La alopecia es un problema hoy en día entre la población, que se define como la disminución o pérdida del cabello, tanto de una manera específica como ...
Quintero Mora, Javier
core  

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source