Results 71 to 80 of about 33,525 (245)
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Hair loss in pediatric inflammatory bowel disease: Clinical recognition and implications for care
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Angela Anaeme +2 more
wiley +1 more source
Emerging Paediatric Uses of Dupilumab Beyond Approvals
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese +11 more
wiley +1 more source
Análise dos Laudos de exames histopatológicos de alopécia em pacientes do Hospital Universitário Polydoro Ernani de São Thiago entre o ano de 2000 e 2005. [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Vegini, Julyan Baum
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BackgroundIncreasing evidence suggests a robust correlation between the gut microbiome and alopecia areata. In light of the extensive diversity of gut microbiota, this study aims to utilize state-of-the-art and comprehensive data to explore the causative
Dezhao Bi +12 more
doaj +1 more source
Summary Background and objectives The financial and time‐related burden of patients with vitiligo remains insufficiently studied. This study aimed to quantify out‐of‐pocket costs (OOPC) and time expenditure for vitiligo management and the associated sociodemographic, clinical, and behavioral factors in German‐speaking countries.
Christine Gasteiger +5 more
wiley +1 more source
Assessment of Interleukin-17A and Interleukin-2 Serum Levels in Patients with Alopecia Areata
Background: Alopecia areata (AA) is a condition that leads to the loss of hair in the part of the body due to the destruction of hair follicles, and causing patchy, non-scarring hair loss.
Sajjad M. Alfadul +2 more
doaj +1 more source
Consensus‐based Guideline on tinea capitis
Summary The consensus‐based guideline developed under the auspices of the German Dermatological Society (DDG) is intended to provide physicians with a structured framework for clinical decision‐making in the management of patients with tinea capitis and to contribute to improved diagnostic accuracy, treatment adherence, and prevention. Tinea capitis is
Peter Mayser +19 more
wiley +1 more source
Patterns of insurance coverage for wigs in patients with alopecia areata: a cross-sectional survey
Ogechi Ezemma, BA +6 more
doaj +1 more source
Alopecia areata universal tratada con ciclosporina via oral Descripción de un caso [PDF]
Se describe un hombre de 46 años, con episodio súbito de alopecia areata universal, con compromiso ungueal. No se detectó factor psicosomático desencadenante. Los estudios paraclínicos fueron normales. Se manejó con ciclos de corticoesteroides sistémicos.
Abreu Vélez , Ana María +1 more
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