Results 71 to 80 of about 1,973 (199)

Molecular signatures define alopecia areata subtypes and transcriptional biomarkers

EBioMedicine, 2016
Alopecia areata (AA) is an autoimmune disease typified by nonscarring hair loss with a variable clinical course. In this study, we conducted whole genome gene expression analysis of 96 human scalp skin biopsy specimens from AA or normal control subjects.
Ali Jabbari, Jane E. Cerise, James C. Chen, Julian Mackay-Wiggan, Madeleine Duvic, Vera Price, Maria Hordinsky, David Norris, Raphael Clynes, Angela M. Christiano   +9 more
doaj   +1 more source

T-helper and natural killer cells’ disturbance in active alopecia areata

Al-Azhar Assiut Medical Journal, 2022
Background and aim Alopecia areata (AA) is a common nonscarring hair disease targeting the hair follicles during the anagen phase, leading to hair loss. The etiology of AA is still unclear; however, evidence revealed the association of this disease with ...
Abdel-Khalek H Younes, Refaat R Hammad, Ali Sobhy   +2 more
doaj   +1 more source

Potential Treatment of Steroid‐Resistant Alopecia Areata Using Allogeneic Exosomes Derived From Adipose Tissue Mesenchymal Stromal Cells: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT A 31‐year‐old man with severe, corticosteroid‐resistant alopecia areata presented with substantial scalp hair loss (Severity of Alopecia Tool [SALT] score: 60%) despite a 1‐year regimen of topical corticosteroids, 5% minoxidil, and oral prednisolone. He was treated with allogeneic exosomes derived from adipose tissue mesenchymal stromal cells (
Masoumeh Kianpisheh, Mohsen Piroozhashemi, Shabnam Feshangchian‐Atashbar, Ali Ghamari, Alireza Shoae‐Hassani   +4 more
wiley   +1 more source

Turban PUVASOL: An effective treatment in alopecia totalis

International Journal of Trichology, 2010
Alopecia areata is characterized by patchy hair loss involving the scalp, eyelashes, and beard. The disease may at times lead to complete baldness of the scalp (alopecia totalis) or of the entire body (alopecia universalis). Alopecia totalis is usually resistant to therapy.
Sornakumar, L, Sekar, C Shanmuga, Srinivas, CR   +2 more
openaire   +3 more sources

S3‐Leitlinie Diagnostik und Therapie der Alopecia areata – Teil 1: Diagnostik und Epidemiologie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 7, Page 1000-1016, July 2026.
Zusammenfassung In dem vom Innovationsausschuss beim gemeinsamen Bundesausschuss (G‐BA) geförderten Projekt wurde von 2023 bis 2025 die S3‐Leitlinie zur Diagnostik und Therapie der Alopecia areata (AA) entwickelt. Die interdisziplinäre Expertengruppe bestand aus Vertretern der Deutschen Dermatologischen Gesellschaft, insbesondere aus der AG ...
Ulrike Blume‐Peytavi, Andria Constantinou, Tsenka Tomova‐Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn   +13 more
wiley   +1 more source

S3 guideline diagnostics and therapy of alopecia areata – Part 1: Diagnostics and epidemiology

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 7, Page e1000-e1015, July 2026.
Summary In the project funded by the Innovation Committee at the G‐BA, the S3 guideline for the diagnosis and treatment of AA was developed between 2023 and 2025. The interdisciplinary expert panel consisted of representatives from the German Dermatological Society, in particular from the Pediatric Dermatology Working Group, the Professional ...
Ulrike Blume‐Peytavi, Andria Constantinou, Tsenka Tomova‐Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn   +13 more
wiley   +1 more source

Alopecia as the first manifestation of azathioprine myelosuppression in a genetically predisposed patient

Indian Journal of Rheumatology, 2019
Azathioprine, an analog of mercaptopurine, is used for various inflammatory/autoimmune diseases in diverse fields such as rheumatology, ophthalmology, gastroenterology, and neurology.
Debashish Mishra, Shefali Khanna Sharma, Aman Sharma, Sanjay Jain, Varun Dhir   +4 more
doaj   +1 more source

Clinical Characteristics, Treatment Patterns, and Outcomes of Chinese Patients With Alopecia Areata: A Retrospective Observational Study

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Alopecia areata (AA) is an inflammatory, nonscarring hair loss disorder with significant variations in the clinical presentation and unpredictable nature of the disease. Although AA is common in clinical dermatology, knowledge gaps remain regarding the clinical characteristics and impact on patients' psychological well‐being and ...
Youyu Sheng, Zhibing Qiu, Jun Zhao, Lijuan Zhou, Ying Miao, Bilian Zhao, Jinnan Li, Guanshen Dou, Wenyu Wu, Qinping Yang   +9 more
wiley   +1 more source

Interleukin-1 Receptor Antagonist Allele 2 and Familial Alopecia Areata [PDF]

, 2002
Alopecia areata affects 1%-2% of the population and is hypothesized to be an autoimmune, organ specific T-cell mediated reaction directed against the human hair follicle.
Barahamani, Nazila, Mariza de Andrade, Nazila Barahamani, Joshua Slusser, de Andrade, Mariza, Slusser, Joshua, Madeleine Duvic, Qing Zhang, Zhang, Qing, Duvic, Madeleine   +9 more
core   +1 more source

A Systematic Review of Literature: TNF‐α Blockers and JAK Inhibitors for the Treatment of Stevens‐Johnson Syndrome, Toxic Epidermal Necrolysis, and Severe Forms of Erythema Multiforme

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Stevens‐Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and erythema multiforme major (EM major) are severe dermatologic conditions characterized by varying degrees of skin detachment and involvement of mucosal membranes, often triggered by drug reactions or infections.
Sadaf Salehi, Pooneh Torabi, Mahsa Abbaspour, Nima Hajizadeh, Sara Sadeghi, Alireza Jafarzadeh, Azadeh Goodarzi   +6 more
wiley   +1 more source