Results 31 to 40 of about 687 (166)

Hairless Gene Nonsense Mutations in Alopecia Universalis: A Case Report

open access: yesIranian Journal of Public Health, 2021
Alopecia universalis (AU) congenital, known as generalized atrichia, is a severe form of autosomal recessive alopecia that results in complete hair loss of scalp and body. Mutations in the human hairless gene (HR) are associated with the phenotype of the
Hamed Heidary   +4 more
doaj   +1 more source

Drug Reaction with eosinophilia and systemic symptoms with alopecia universalis and vitiligo

open access: yesMedicina, 2021
Drug reactions with eosinophilia and systemic symptoms (DRESS) are rare and potentially fatal adverse hypersensitivity reaction to some drugs, especially anticonvulsants. The syndrome affects not only the skin but also other organs, especially the liver.
Ives Alexandre Yutani Koseki   +5 more
doaj  

Successful treatment of concomitant alopecia universalis and Crohn’s disease with upadacitinib: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Alopecia areata is a non-scarring, autoimmune hair loss disorder that is associated with inflammatory bowel disease. Alopecia areata and inflammatory bowel disease may have a common pathogenic mechanism that involves the Janus kinase/STAT pathway.
Leah A Johnston   +2 more
doaj   +1 more source

Peripheral neuropathy associated with tofacitinib use in alopecia universalis

open access: yesJournal of Dermatology and Dermatologic Surgery, 2022
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. Alopecia universalis (AU) is the advanced form of AA characterized by complete scalp and body hair loss.
Raghad Alharthi   +4 more
doaj   +1 more source

Atrichia with papular lesions: A case report

open access: yesSAGE Open Medical Case Reports, 2020
We present a case of clinically suspected atrichia with papular lesions in an 8-year-old male presenting with alopecia universalis and keratotic papules. We review the literature available on this rare genodermatosis.
Lauren Curry, Kyle Cullingham
doaj   +1 more source

Comparison of the Treatment Outcome of Oral Tofacitinib with Other Conventional Therapies in Refractory Alopecia Totalis and Universalis: A Retrospective Study

open access: yesActa Dermato-Venereologica, 2018
Treatment of alopecia totalis and alopecia universalis is often challenging and unsatisfactory. Recently, Janus kinase inhibitor has shown promising results.
Jung-Won Shin   +6 more
doaj   +1 more source

Cyclosporine With and Without Systemic Corticosteroids in Treatment of Alopecia Areata: A Systematic Review

open access: yesDermatology and Therapy, 2020
Introduction Cyclosporine is commonly used in treatment for alopecia areata. It can be administered as a monotherapy or in combination with systemic corticosteroids, with various outcomes.
Joanna Nowaczyk   +4 more
doaj   +1 more source

Multiomics Analysis of the Response to Ritlecitinib in Alopecia Areata Subtypes and Correlation With Efficacy

open access: yesAllergy, EarlyView.
Ritlecitinib modulated Type I/II immunity genes (CCL5, CD8A, GZMB, CCL13, CCL18, and IL13RA1), MoA genes (JAK3, ITK, and BTK), and upregulated hair keratins, with stronger effects in AAP than AT/AU. Baseline and longitudinal scalp and serum protein changes correlated with hair regrowth and disease improvement.
Li Xi   +6 more
wiley   +1 more source

Unexpected hair regrowth in a woman with longstanding Alopecia universalis

open access: yesGMS Ophthalmology Cases, 2021
Alopecia areata (AA) is an autoimmune disorder leading to non-scarring hair loss. As long as hair follicles are not destroyed, the potential for hair regrowth remains.
Akritidou, Fani   +4 more
doaj   +1 more source

Clinical heterogeneity in vitiligo: Identification of clinical markers based patient clusters

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Vitiligo is a chronic autoimmune disease with heterogeneous clinical presentations. This study analysed 399 patients using hierarchical clustering and identified five phenotypes based on clinical characteristics and lesion distribution. Two groups exhibited high disease activity and extensive involvement.
Laura Galissi   +8 more
wiley   +1 more source

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