Results 91 to 100 of about 30,248,737 (228)

The delay effect of sulfur mustard gas on phenotype and plasma alpha-1-antitrypsin activity in war victim patients

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2010
Background and Objective: Alpha-1 antitrypsin deficiency is recognized as a etiological base in lung injury. Therefore this study was performed to determine plasma level of alpha-1 antitrypsin in war victims exposed to sulfur mustard gas.
Majid Shohrati (PhD)   +3 more
doaj  

Deficiency of α-1-antitrypsin influences systemic iron homeostasis

open access: yes, 2013
Andrew J Ghio,1 Joleen M Soukup,1 Judy H Richards,1 Bernard M Fischer,2 Judith A Voynow,2 Donald E Schmechel31US Environmental Protection Agency, Chapel Hill, NC, USA; 2Division of Pediatric Pulmonary Medicine, Department of Pediatrics,3Joseph and ...
Soukup JM   +5 more
core  

Drug‐Induced Liver Injury During Treatment With Tocilizumab: A Case Report of an Atypical Pattern Lesion

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Tocilizumab is an interleukin‐6 (IL‐6) receptor antagonist indicated for various rheumatologic conditions. While hepatotoxicity is a recognized adverse effect, it predominantly manifests as hepatocellular injury. We report a rare case of drug‐induced liver injury (DILI) presenting with a cholestatic pattern and cholangitis features in a 75 ...
Louis‐Edmond Barbaro   +7 more
wiley   +1 more source

Chaotropic Surface Arginine Correlates With Protein Corona Formation on Anti‐Fouling Biomaterial Surfaces: A Quantitative Proteomics and Protein Structure Study

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 17, 8 September 2026.
Why do specific proteins accumulate on “non‐fouling” surfaces? Quantitative proteomics and structural analysis reveal surface‐exposed arginine as the key molecular determinant. ABSTRACT The protein corona determines the biocompatibility of medical devices, yet predicting its composition on anti‐fouling surfaces remains challenging.
Ayano Nomura   +5 more
wiley   +1 more source

Prolonged VV‐ECMO as a Bridge to Recovery From Persistent Hepatopulmonary Syndrome After Liver Transplantation: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT In persistent HPS‐related hypoxemia after LT, prolonged VV‐ECMO can serve as a bridge to recovery when conventional oxygenation strategies fail. Serial contrast‐enhanced echocardiography and multidisciplinary management may support weaning decisions and the management of ECMO‐related complications.
Paweł Topolewski   +9 more
wiley   +1 more source

Serum Alpha-1 Antitrypsin Levels and the Clinical Course of Chronic Obstructive Pulmonary Disease

open access: yesInternational Journal of COPD, 2019
Nozomu Takei,1,* Masaru Suzuki,1,* Hironi Makita,2 Satoshi Konno,1 Kaoruko Shimizu,1 Hiroki Kimura,1 Hirokazu Kimura,1 Masaharu Nishimura1,2 1Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University ...
Takei N   +7 more
doaj  

Successful Outcome and Biliary Drainage in an Infant with Concurrent Alpha-1-Antitrypsin Deficiency and Biliary Atresia

open access: yesCase Reports in Surgery, 2017
We describe the rare instance of concomitant biliary atresia and alpha-1-antitrypsin deficiency and the first documented successful portoenterostomy in this scenario.
Andrew W. Wang   +2 more
doaj   +1 more source

Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency

open access: yes, 2009
Irina Petrache1, Joud Hajjar1, Michael Campos21Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; 2Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Miller School of Medicine ...
Campos, Michael   +5 more
core  

Large Undifferentiated Sarcoma of the Liver: A Rare Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Undifferentiated embryonal sarcoma of the liver (UESL) is a rare pediatric malignancy requiring prompt histopathological diagnosis. Neoadjuvant chemotherapy followed by extended right hepatectomy can achieve complete tumor necrosis with negative margins. A multidisciplinary approach is essential for favorable outcomes in pediatric UESL.
Hanzala Zahid   +7 more
wiley   +1 more source

Generation and characterisation of transgenic zebrafish expressing human alpha-1-antitrypsin

open access: yes, 2017
The Z variant of α1-antitrypsin (Z-AAT) is the most common “severe” deficiency allele of α1-antitrypsin. It affects approximately 2% to 5% of Caucasians of European descent [1-3].
Yip, Evelyn Lai Si (3770644)
core   +1 more source

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