Results 121 to 130 of about 410,523 (291)

Alpha 1 Antitrypsin Deficiency Pathophysiology, Symptoms, Diagnosis, Treatment

open access: yesQuality in Sport
Introduction: This review paper aims to emphasize how Alpha-1-antitrypsin deficiency is how can lead to serious disease states, indicating the pathophysiology, symptoms, diagnostic possibilities, therapeutic methods and proving that early diagnostics for
Kamil Kościelecki   +9 more
doaj   +1 more source

Alpha 1-antitrypsin retention in an ectopic liver

open access: yesDiagnostic Pathology, 2011
Ectopic livers are infrequently reported in the literature. The reported size for ectopic livers range from a few millimeters up to several centimeters.
Cathomas Gieri   +2 more
doaj   +1 more source

SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency

open access: yesJournal of Nucleic Acids, 2018
Alpha-1-antitrypsin (AAT) deficiency is a genetic disorder that produces inactive/defective AAT due to mutations in the SERPINA1 gene encoding AAT.
B. Connolly   +4 more
semanticscholar   +1 more source

Elevated serum aminotransferases in an infant with failure to thrive: A clinicopathological case report

open access: yes
JPGN Reports, EarlyView.
Jamie M. Klapp   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

A comparative proteomic analysis of bile for biomarkers of cholangiocarcinoma

open access: yesTumor Biology, 2017
Cholangiocarcinoma is a primary malignant tumor of the bile duct epithelium. Cholangiocarcinoma is usually detected at an advanced stage when successful treatment is no longer possible.
Marut Laohaviroj   +8 more
doaj   +1 more source

Measurement of the Proteinase Inhibitors of the Bovine Pancreas by Radioimmunoassay [PDF]

open access: yes, 1976
Bovine pancreas contains two polypeptide trypsin inhibitors that are not homologous and differ in their inhibitory activity towards chymotrypsin, kallikrein, elastase, and other serine proteinases. The Kunitz inhibitor and the Kazal inhibitor are present
Fink, Edwin   +2 more
core   +1 more source

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh   +11 more
wiley   +1 more source

Key inflammatory pathway activations in the MCI stage of Alzheimer's disease [PDF]

open access: yes, 2019
OBJECTIVE: To determine the key inflammatory pathways that are activated in the peripheral and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer's disease (AD).
Bekris, Lynn M.   +7 more
core   +2 more sources

Reduced Dietary Protein Induces Changes in the Dental Proteome

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs   +2 more
wiley   +1 more source

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