Эндоцитозный путь альфа-фетопротеина в гемопоэтических стволовых клетках костного мозга мышей: молекулярная характеристика и роль в изменении биологической активности [PDF]
, 2014 оцитозный путь альфа-фетопротеина (АФП) в трех различных по степени зрелости типах гемопоэтических стволовых клеток (ГСК) костного мозга мышей являлся схожим по своей природе: его основу составлял рецептор-опосредованный транспорт, через мембранные р60 ...
Богданов, А.Ю. +2 more
core +1 more source
Cabozantinib in hepatocellular carcinoma: results of a phase 2 placebo-controlled randomized discontinuation study. [PDF]
, 2017 BackgroundCabozantinib, an orally bioavailable inhibitor of tyrosine kinases including MET, AXL, and VEGF receptors, was assessed in patients with hepatocellular carcinoma (HCC) as part of a phase 2 randomized discontinuation trial with nine tumor-type ...
Braiteh, F +11 more
core
Binding characterization of the targeting drug AIMPILA to AFP receptors in human tumor xenografts
Tumor Biology, 2017 The main objective of this study was the characterization of preclinical tumor models based on their expression of alpha-fetoprotein receptor (RECAF) for targeting cancer cells with a new non-covalent complex (AIMPILA) containing alpha-fetoprotein as the
Janneta Tcherkassova +5 more
doaj +1 more source
Platelet-to-lymphocyte ratio in the setting of liver transplantation for hepatocellular cancer. A systematic review and meta-analysis [PDF]
, 2018 AIM: To perform a systematic review and meta-analysis on platelet-to-lymphocyte ratio (PLR) as a risk factor for post-transplant hepatocellular cancer (HCC) recurrence. METHODS: A systematic literature search was performed using PubMed.
Corradini, Stefano Ginanni +8 more
core +1 more source
Urine tests for Down's syndrome screening [PDF]
, 2015 Background Down's syndrome occurs when a person has three copies of chromosome 21, or the specific area of chromosome 21 implicated in causing Down's syndrome, rather than two.
Abbas +524 more
core +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.Correlation matrix analysis of lymphocyte parameters. The correlation matrix showed the positive (red) or negative (blue) correlation of two parameters; the color intensity reflected the correlation coefficient. Conducting lymphocyte testing in health management can help monitor immune status, evaluate health risks, analyze pathogenesis of diseases ...
An‐Na Jiang +5 more
wiley +1 more source
Expression and function of osteopontin variants in HCV-related liver disease and hepatocellular carcinoma. [PDF]
, 2010 Osteopontin (OPN) is a highly secreted multi-functional sialoprotein that is widely expressed in tissues, blood and urine. It is involved in a number of normal physiological functions, but is also significantly elevated in a number of cancers.
Phillips, Renee Jade
core +1 more source
Youngest known case of a pancreatic perivascular epithelioid cell tumor
JPGN Reports, EarlyView.Abstract Perivascular epithelioid cell tumors (PEComas) are a rare type of mesenchymal tumor that can arise in any part of the body. As of 2024, 37 cases of pancreatic PEComas had been reported in the literature with patients ranging in age from 17 to 74 years old.
Laura Gilligan +5 more
wiley +1 more source
Vascular Endothelial Growth Factor Level as a Predictor of Hepatocellular Carcinoma in Liver Cirrhosis Patients [PDF]
, 2014 BACKGROUND: Alpha-fetoprotein (AFP) has been used for hepatocellular carcinoma (HCC) diagnosis and screening, however, AFP has poor specificity. The extensive hypervascularity associated with HCC could be driven in part by the pro-angiogenic factor known
Lukito, B. (Benyamin) +7 more
core +4 more sources