Results 131 to 140 of about 74,736 (296)
Alimentary Pharmacology &Therapeutics, EarlyView.Alpha‐1 antitrypsin deficiency is a genetic disease that affects the lungs and the liver. The role of the heterozygous genetic defect in the development of liver cancer in patients with cirrhosis is unclear. Our study found that carrying the Pi*MZ genotype increases the risk of developing liver cancer.
Lorenz Balcar +18 more
wiley +1 more source
Effects of serum-clot contact time on second-trimester prenatal screening markers and their stability in serum [PDF]
Journal of Medical Biochemistry, 2010 Alpha-fetoprotein, human chorionic gonadotropin and unconjugated estriol are screening markers for fetal trisomies and structural disorders of the neural tube defect type.
Bujišić Nada
doaj
Reproductive tract biology: Of mice and men. [PDF]
, 2019 The study of male and female reproductive tract development requires expertise in two separate disciplines, developmental biology and endocrinology.
Baskin, Laurence S +5 more
core
Guideline of guidelines: management of small testicular masses
BJU International, EarlyView.Objective To compare and summarise the most up to date international guidelines and major recommendations for the management of small testicular masses (STMs). Methods A systematic search was conducted in PubMed, EMBASE, Scopus, Google Scholar, and the Cochrane Library up to 1 November 2024.
Marco Tozzi +7 more
wiley +1 more source
Cancer Science, EarlyView.SPP1 was identified as a key driver of intratumoral fibrosis and hepatocellular carcinoma (HCC) progression through transcriptomic, histological, and functional analyses. Mechanistically, SPP1 promotes HSC activation and fibrosis via the SPP1–CD44–GLI1 axis, and pharmacologic inhibition of Hedgehog signaling effectively reduces tumor growth and ...
Atsushi Nara +16 more
wiley +1 more source
A Closer Look at the Global Management of Spina Bifida: The Implementation of Endoscopic Third Ventriculostomy in the Treatment of Spina Bifida-Related Hydrocephalus in Africa [PDF]
, 2018 Spina bifida, specifically myelomeningocele, is a debilitating neural tube defect that affects patients and families throughout the world. Traditional management and treatment methods are described, followed by an explanation of why this is often ...
Burckart, Caryssa
core +1 more source
Hepatology Research, EarlyView.In this real‐world post‐ICI setting, cabozantinib demonstrated meaningful clinical activity even at reduced doses, with disease control achieved in nearly half of patients. Importantly, preserved liver function (Child–Pugh class A) was the only determinant of both disease control and overall survival.
Teiji Kuzuya +13 more
wiley +1 more source
The Prognostic Value of Alpha-Fetoprotein Response for Advanced-Stage Hepatocellular Carcinoma Treated with Sorafenib Combined with Transarterial Chemoembolization [PDF]
, 2016 Lei Liu +15 more
openalex +1 more source
Hepatology Research, EarlyView.ABSTRACT Background There is a paucity of data regarding the efficacy and safety of lenvatinib as a second‐line treatment following first‐line combination immunotherapy with durvalumab and tremelimumab (Dur + Tre). Methods This retrospective multicenter study included 14 patients with unresectable hepatocellular carcinoma who received lenvatinib after ...
Ryoichi Miura +21 more
wiley +1 more source