Results 181 to 190 of about 49,741 (289)

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

Advanced Science, Volume 12, Issue 39, October 20, 2025.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang, Chengming Gao, Haibei Li, Yuying Chen, Liting Yang, Qian Jin, Lan Feng, Xia Wang, Xinyi Liu, Hongxia Chen, Rong Ye, Yuanchao Xue, Huiyun Wang, Musheng Zeng, Ming Yang, Huaiqiang Ju, Chengzhi Gao, Guangming Zhou, Qi Zhang, Qian Zhang, Geng Qin, Yuanfeng Li, Yahui Wang, Aiqing Yang, Anfeng Si, Qingfeng Song, Fuchu He, Pengbo Cao, Gangqiao Zhou   +28 more
wiley   +1 more source

Mouse alpha 1-fetoprotein and albumin. A comparison of their binding properties with estrogen and fatty acid ligands.

, 1981
Lia Savu, C. Benassayag, G. Vallette, N. Christeff, E.A. Nunez   +4 more
openalex   +1 more source

Video‐Assisted Thoracoscopic Removal of a Mediastinal Mass in a Newborn: A Case Report

Journal of Paediatrics and Child Health, EarlyView.
Carlo Maria Ferlini, Alessia Arossa, Claudia Codazzi, Stefano Ghirardello, Simonetta Mencherini, Luca Lungarotti, Giovanna Riccipetitoni, Mirko Bertozzi   +7 more
wiley   +1 more source

Addressing the Diagnostic Odyssey for Adults With Neurodevelopmental Disabilities: Case Study of an Individual With Mandibulofacial Dysostosis With Microcephaly

American Journal of Medical Genetics Part A, Volume 197, Issue 10, October 2025.
ABSTRACT Whole exome sequencing (WES) has been widely used in the pediatric setting to increase diagnostic yield, provide treatment options, and to estimate reoccurrence risks. However, there is limited knowledge regarding the utility of this technology in adults with neurodevelopmental disabilities.
Ruhi Shah, Neora Shifrin, Mary Ellen Keogh, Elaine Marchi, Maureen Gavin, Karen Amble, Gholson J. Lyon   +6 more
wiley   +1 more source

Rapid Detection of Alpha-Fetoprotein (AFP) with Lateral Flow Aptasensor. [PDF]

Molecules
Ma M, Zhang M, Wang J, Zhou Y, Zhang X, Liu G.   +5 more
europepmc   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, Volume 5, Issue 10, October 2025.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source

Evaluating the combined diagnostic power of alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II for hepatocellular carcinoma. [PDF]

J Gastrointest Oncol
Zhang S, Gao C, Wang Y, Chen L, Gao S.
europepmc   +1 more source

Human tissue‐type plasminogen activator is related to albumin and alpha‐fetoprotein [PDF]

, 1985
Michael E. Baker
openalex   +1 more source

Coordinated gene expression within sustained STAT3‐associated chromatin conformations contributes to hepatocellular carcinoma progression

Cancer Communications, Volume 45, Issue 10, Page 1309-1333, October 2025.
Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang, Sumin Yoon, Hyeokjun Yang, Nayun Choi, Su‐Hyang Han, Lark Kyun Kim, Hyoung‐Pyo Kim, Jong Hoon Park, Daeyoup Lee, Kyung Hyun Yoo   +9 more
wiley   +1 more source

Kupffer Phase Radiomics Signature in Sonazoid Contrast‐Enhanced Ultrasound Predicts Immunohistochemistry Marker Expression in Hepatocellular Carcinoma

Cancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Purpose Few studies have explored the value of radiomics signatures in predicting immunohistochemical (IHC) staining markers. This study aimed to investigate and validate radiomics models based on the Kupffer phase of Sonazoid contrast‐enhanced intraoperative ultrasonography (S‐CEUS) images for predicting IHC marker expression in ...
Chen Li, Yuan Liu, Mingxiao Wu, Weide Dai, Jinghai Song, Yong Wang   +5 more
wiley   +1 more source